<html><body style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space; ">
<div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font class="Apple-style-span" face="Monaco" size="3"><span class="Apple-style-span" style="font-size: 13px;"><br></span></font></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><span class="Apple-style-span" style="font-family: Monaco; font-size: 13px; ">Good afternoon,</span></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font class="Apple-style-span" face="Monaco" size="3"><span class="Apple-style-span" style="font-size: 13px;"><br></span></font></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font face="Monaco" size="4" style="font: 13.0px Monaco">We are currently writing registration code to handle mono-modality and multi-modality image registration using CT and MR data-sets.</font></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font class="Apple-style-span" face="Monaco" size="3"><span class="Apple-style-span" style="font-size: 13px;"><br></span></font></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font class="Apple-style-span" face="Monaco" size="3"><span class="Apple-style-span" style="font-size: 13px;">At the present time, the code is able to perform registration using both of these data-sets. The fixed-image is two-dimensional (treated as three-dimensional image-type by the code) and the moving-image is a volume created from a sequence of two-dimensional DICOM slices.</span></font></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font class="Apple-style-span" face="Monaco" size="3"><span class="Apple-style-span" style="font-size: 13px;"><br></span></font></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font class="Apple-style-span" face="Monaco" size="3"><span class="Apple-style-span" style="font-size: 13px;">Using the itk::ImageSeriesReader class, mono-modality CT registration requires the SetReverseOrder method of this class to be called with a "true" boolean value and MR registration requires a "false" boolean value when the respective volumes are created.</span></font></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font class="Apple-style-span" face="Monaco" size="3"><span class="Apple-style-span" style="font-size: 13px;"><br></span></font></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font class="Apple-style-span" face="Monaco" size="3"><span class="Apple-style-span" style="font-size: 13px;">I have ensured that the maximum-step used by the optimizer is properly set in both cases.</span></font></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font class="Apple-style-span" face="Monaco" size="3"><span class="Apple-style-span" style="font-size: 13px;"><br></span></font></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font class="Apple-style-span" face="Monaco" size="3"><span class="Apple-style-span" style="font-size: 13px;">I believe the root of this requirement lies in the meta-data of the DICOM images that comprise the CT and MR data-sets, but I do not know why or what to look for in order to help find an answer.</span></font></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font class="Apple-style-span" face="Monaco" size="3"><span class="Apple-style-span" style="font-size: 13px;"><br></span></font></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font class="Apple-style-span" face="Monaco" size="3"><span class="Apple-style-span" style="font-size: 13px;">I have not used ITK extensively and this is my first experience with image-processing.</span></font></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font class="Apple-style-span" face="Monaco" size="3"><span class="Apple-style-span" style="font-size: 13px;"><br></span></font></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font class="Apple-style-span" face="Monaco" size="3"><span class="Apple-style-span" style="font-size: 13px;"><br></span></font></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font class="Apple-style-span" face="Monaco" size="3"><span class="Apple-style-span" style="font-size: 13px;"><br></span></font></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font class="Apple-style-span" face="Monaco" size="3"><span class="Apple-style-span" style="font-size: 13px;">Any help is greatly appreciated,</span></font></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font class="Apple-style-span" face="Monaco" size="3"><span class="Apple-style-span" style="font-size: 13px;"><br></span></font></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font class="Apple-style-span" face="Monaco" size="3"><span class="Apple-style-span" style="font-size: 13px;"><br></span></font></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font class="Apple-style-span" face="Monaco" size="3"><span class="Apple-style-span" style="font-size: 13px;">Michael.</span></font></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font class="Apple-style-span" face="Monaco" size="3"><span class="Apple-style-span" style="font-size: 13px;"><br></span></font></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font class="Apple-style-span" face="Monaco" size="3"><span class="Apple-style-span" style="font-size: 13px;">Michael Wirtzfeld</span></font></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font class="Apple-style-span" face="Monaco" size="3"><span class="Apple-style-span" style="font-size: 13px;">Robarts Research</span></font></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><font class="Apple-style-span" face="Monaco" size="3"><span class="Apple-style-span" style="font-size: 13px;"><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><br></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; ">"Prefer the standard to the offbeat." - Strunk & White</div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><br></div></span></font></div></body></html>