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Hi guys -<br>
<br>
This is more of a question than a suggestion: does ITK currently
support "pixel padding"? That is, can we currently define a value in
the image data that serves as a marker for pixels that aren't really
there? Think of it as a binary mask coded into the image itself.<br>
<br>
In my experience, when you register partial objects to complete
objects (also interesting to register skull-stripped brains to full
head images, for example), the key is to be able to exclude pixels
from the metric computation altogether, rather than just setting
them to zero.<br>
<br>
Alternatively, because we cannot always find a pixel value that
isn't actually used by the data already, one could implement this
behaviour by providing the registration framework with optional
explicit binary masks for fixed and moving images.<br>
<br>
Best,<br>
Torsten<br>
<br>
<blockquote type="cite">
<pre>Hello Erik
You may want to try changing the number of resolutions employed in the
multi-resolution pyramid used to perform the registration. In
addition, you may want to try switching the role of the fixed/moving
image. We are currently revising the registration framework so now is
a good time to bring these types of issues up and work with us on
improving registration performance.
Brian
On Thu, Oct 21, 2010 at 4:35 AM, Erik Tuerke <<a href="http://www.itk.org/mailman/listinfo/insight-users">tuerke at cbs.mpg.de</a>> wrote:
><i> Hi!
</i>><i>
</i>><i> I want to register one hemisphere (actually 30 slices of 0.75 mm) to a
</i>><i> fullbrain scan (30 slices of 0.75mm, but shifted to superior for about 5 mm)
</i>><i> . Currently i am using a MattesMutualInformationImageToImage metric, a
</i>><i> RegularStepGradientDescentOptimizer and a VersorRigid3DTransform.
</i>><i>
</i>><i> Prior to the registration the hemisphere is roughly aligned to the fullbrain
</i>><i> (only needs translation of few mm and little rotation). If i start the
</i>><i> registration the optimizer finishes with a rotation of about 90 deg x and y.
</i>><i> I also tried a VersorRigid3DOptimizer and a NormalizedCorrelation with
</i>><i> almost the same result.
</i>><i>
</i>><i> The scalefactors of my optimizer are:
</i>><i> optimizerScaleRegularStepGradient[0] = 1.0;
</i>><i> optimizerScaleRegularStepGradient[1] = 1.0;
</i>><i> optimizerScaleRegularStepGradient[2] = 1.0;
</i>><i> optimizerScaleRegularStepGradient[3] = 1.0/1000.0;
</i>><i> optimizerScaleRegularStepGradient[4] = 1.0/1000.0;
</i>><i> optimizerScaleRegularStepGradient[5] = 1.0/1000.0;
</i>><i>
</i>><i> I guess the itk examples are proposing the same values.
</i>><i> Is there any trick to apply such a sub-brain registration to a full-brain
</i>><i> registration. The worrying thing is that SPM gets it right :-(
</i>><i>
</i>><i> Thanks and best regards!!
</i>><i>
</i>><i> --
</i>><i> Erik Tuerke
</i>><i> Department of Neurophysics Max-Planck-Institute for Human Cognitive and
</i>><i> Brain Sciences
</i>><i> Stephanstrasse 1A
</i>><i> 04103 Leipzig
</i>><i> Germany Tel: +49 341 99 40-2440
</i>><i> Email: <a href="http://www.itk.org/mailman/listinfo/insight-users">tuerke at cbs.mpg.de</a>
</i>><i> <a class="moz-txt-link-abbreviated" href="http://www.cbs.mpg.de">www.cbs.mpg.de</a>
</i>><i>
</i>><i>
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</pre>
</blockquote>
<br>
<pre class="moz-signature" cols="72">--
Torsten Rohlfing, PhD SRI International, Neuroscience Program
Senior Research Scientist 333 Ravenswood Ave, Menlo Park, CA 94025
Phone: ++1 (650) 859-3379 Fax: ++1 (650) 859-2743
<a class="moz-txt-link-abbreviated" href="mailto:torsten@synapse.sri.com">torsten@synapse.sri.com</a> <a class="moz-txt-link-freetext" href="http://www.stanford.edu/~rohlfing/">http://www.stanford.edu/~rohlfing/</a>
"Though this be madness, yet there is a method in't"
</pre>
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