Hi all,<div><br></div><div>I am currently working in Breast MRI registration between different patients, especially interested in the alignment of body area (thorax + pectoral muscles). The first step of my registration consist of a translation to align the sternum, which gives a good initial alignment of the pectoral muscles. In the following link you can see an example of one slice with the sternum indicated with a white cross: <a href="http://imageshack.us/photo/my-images/220/breastmristernum.png/">http://imageshack.us/photo/my-images/220/breastmristernum.png/</a>. After the translation step with the pectorals already "rigidly" aligned I apply non-rigid b-splines registration to the whole volumes. It works well in some cases, but in others, especially of course when the differences are high between fixed and moving images, the non-rigid registration move the sternum point and the pectorals are not aligned anymore. </div>
<div><br></div><div>I have thought that not allowing the non-registration the move of the sternum point and the ones close to it could be a good solution for such problem. However, I have taken a look to the classes and the mailing list but I have not found any direct/easy example to how to do that. </div>
<div><br></div><div>Could anyone give me some advice? Does a easy way to do it exist or I should modify the classes involved in the registration framework? Which ones should I take a look? </div><div><br></div><div>Thanks in advance,</div>
<div><br></div><div>Albert</div><meta http-equiv="content-type" content="text/html; charset=utf-8">