<br><div>Dear List Users,</div><div><br></div><div><br></div><div>I have been trying to perform deformable registration using the thin plate spline transform. I understand how thin plate splines work in the context of mathematics but I do not understand how it is employed for registration purposes. Could somebody explain to me the theoretical aspect of how thin plate spline can be used for registration? I have gone through the paper mentioned in the code for thinplatesplinekerneltransform, but that explains only the mathematical concepts, it does not say how a spline used to represent the set of source landmarks can give the target landmarks. Is a displacement applied to the spline as a whole? or are different weights applied to different regions of the spline to displace it?</div>
<div><br></div><div>Hope somebody can explain this to me.</div><div><br></div><div><br></div><div>Thanks a lot</div><div>Lisa</div>