RegistrationITKv4/ImageRegistration9.cxx

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 *
 *  Copyright Insight Software Consortium
 *
 *  Licensed under the Apache License, Version 2.0 (the "License");
 *  you may not use this file except in compliance with the License.
 *  You may obtain a copy of the License at
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 *         http://www.apache.org/licenses/LICENSE-2.0.txt
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 *  distributed under the License is distributed on an "AS IS" BASIS,
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//  Software Guide : BeginCommandLineArgs
//    INPUTS:  {BrainProtonDensitySliceBorder20.png}
//    INPUTS:  {BrainProtonDensitySliceR10X13Y17.png}
//    OUTPUTS: {ImageRegistration9Output.png}
//    OUTPUTS: {ImageRegistration9DifferenceBefore.png}
//    OUTPUTS: {ImageRegistration9DifferenceAfter.png}
//    ARGUMENTS:    1.0 300
//  Software Guide : EndCommandLineArgs

// Software Guide : BeginLatex
//
// This example illustrates the use of the \doxygen{AffineTransform}
// for performing registration in $2D$. The example code is, for the most part,
// identical to that in \ref{sec:InitializingRegistrationWithMoments}.
// The main difference is the use of the AffineTransform here instead of the
// \doxygen{CenteredRigid2DTransform}. We will focus on the most
// relevant changes in the current code and skip the basic elements already
// explained in previous examples.
//
// \index{itk::AffineTransform}
//
// Software Guide : EndLatex

#include "itkImageRegistrationMethodv4.h"
#include "itkMeanSquaresImageToImageMetricv4.h"
#include "itkRegularStepGradientDescentOptimizerv4.h"


#include "itkCenteredTransformInitializer.h"

//  Software Guide : BeginLatex
//
//  Let's start by including the header file of the AffineTransform.
//
//  \index{itk::AffineTransform!header}
//
//  Software Guide : EndLatex

// Software Guide : BeginCodeSnippet
#include "itkAffineTransform.h"
// Software Guide : EndCodeSnippet


#include "itkImageFileReader.h"
#include "itkImageFileWriter.h"

#include "itkResampleImageFilter.h"
#include "itkCastImageFilter.h"
#include "itkSubtractImageFilter.h"
#include "itkRescaleIntensityImageFilter.h"


//
//  The following piece of code implements an observer
//  that will monitor the evolution of the registration process.
//
#include "itkCommand.h"
class CommandIterationUpdate : public itk::Command
{
public:
  typedef  CommandIterationUpdate   Self;
  typedef  itk::Command             Superclass;
  typedef itk::SmartPointer<Self>   Pointer;
  itkNewMacro( Self );

protected:
  CommandIterationUpdate() {};

public:
  typedef itk::RegularStepGradientDescentOptimizerv4<double>  OptimizerType;
  typedef   const OptimizerType *                             OptimizerPointer;

  void Execute(itk::Object *caller, const itk::EventObject & event)
    {
    Execute( (const itk::Object *)caller, event);
    }

  void Execute(const itk::Object * object, const itk::EventObject & event)
    {
    OptimizerPointer optimizer =
                      dynamic_cast< OptimizerPointer >( object );
    if( ! itk::IterationEvent().CheckEvent( &event ) )
      {
      return;
      }
      std::cout << optimizer->GetCurrentIteration() << "   ";
      std::cout << optimizer->GetValue() << "   ";
      std::cout << optimizer->GetCurrentPosition();

      // Print the angle for the trace plot
      vnl_matrix<double> p(2, 2);
      p[0][0] = (double) optimizer->GetCurrentPosition()[0];
      p[0][1] = (double) optimizer->GetCurrentPosition()[1];
      p[1][0] = (double) optimizer->GetCurrentPosition()[2];
      p[1][1] = (double) optimizer->GetCurrentPosition()[3];
      vnl_svd<double> svd(p);
      vnl_matrix<double> r(2, 2);
      r = svd.U() * vnl_transpose(svd.V());
      double angle = std::asin(r[1][0]);
      std::cout << " AffineAngle: " << angle * 180.0 / vnl_math::pi << std::endl;
    }
};


int main( int argc, char *argv[] )
{
  if( argc < 4 )
    {
    std::cerr << "Missing Parameters " << std::endl;
    std::cerr << "Usage: " << argv[0];
    std::cerr << "   fixedImageFile  movingImageFile " << std::endl;
    std::cerr << "   outputImagefile  [differenceBeforeRegistration] " << std::endl;
    std::cerr << "   [differenceAfterRegistration] " << std::endl;
    std::cerr << "   [stepLength] [maxNumberOfIterations] "<< std::endl;
    return EXIT_FAILURE;
    }


  //  Software Guide : BeginLatex
  //
  //  We define then the types of the images to be registered.
  //
  //  Software Guide : EndLatex

  // Software Guide : BeginCodeSnippet
  const    unsigned int    Dimension = 2;
  typedef  float           PixelType;

  typedef itk::Image< PixelType, Dimension >  FixedImageType;
  typedef itk::Image< PixelType, Dimension >  MovingImageType;
  // Software Guide : EndCodeSnippet


  //  Software Guide : BeginLatex
  //
  //  The transform type is instantiated using the code below. The template
  //  parameters of this class are the representation type of the space
  //  coordinates and the space dimension.
  //
  //  \index{itk::AffineTransform!Instantiation}
  //
  //  Software Guide : EndLatex

  // Software Guide : BeginCodeSnippet
  typedef itk::AffineTransform< double, Dimension  > TransformType;
  // Software Guide : EndCodeSnippet


  typedef itk::RegularStepGradientDescentOptimizerv4<double>       OptimizerType;
  typedef itk::MeanSquaresImageToImageMetricv4<
                                          FixedImageType,
                                          MovingImageType >        MetricType;
  typedef itk::ImageRegistrationMethodv4<
                                  FixedImageType,
                                  MovingImageType,
                                  TransformType >                   RegistrationType;

  MetricType::Pointer         metric        = MetricType::New();
  OptimizerType::Pointer      optimizer     = OptimizerType::New();
  RegistrationType::Pointer   registration  = RegistrationType::New();

  registration->SetMetric(        metric        );
  registration->SetOptimizer(     optimizer     );


  //  Software Guide : BeginLatex
  //
  //  The transform object is constructed below and is initialized before registration
  //  process starts.
  //
  //  \index{itk::AffineTransform!New()}
  //  \index{itk::AffineTransform!Pointer}
  //  \index{itk::RegistrationMethodv4!SetTransform()}
  //
  //  Software Guide : EndLatex

  // Software Guide : BeginCodeSnippet
  TransformType::Pointer  transform = TransformType::New();
  // Software Guide : EndCodeSnippet


  typedef itk::ImageFileReader< FixedImageType  > FixedImageReaderType;
  typedef itk::ImageFileReader< MovingImageType > MovingImageReaderType;
  FixedImageReaderType::Pointer  fixedImageReader  = FixedImageReaderType::New();
  MovingImageReaderType::Pointer movingImageReader = MovingImageReaderType::New();
  fixedImageReader->SetFileName(  argv[1] );
  movingImageReader->SetFileName( argv[2] );


  registration->SetFixedImage(    fixedImageReader->GetOutput()    );
  registration->SetMovingImage(   movingImageReader->GetOutput()   );


  //  Software Guide : BeginLatex
  //
  //  In this example, we again use the
  //  \doxygen{CenteredTransformInitializer} helper class in order to compute
  //  reasonable values for the initial center of rotation and the
  //  translations. The initializer is set to use the center of mass of each
  //  image as the initial correspondence correction.
  //
  //  Software Guide : EndLatex

  // Software Guide : BeginCodeSnippet
  typedef itk::CenteredTransformInitializer<
                                        TransformType,
                                        FixedImageType,
                                        MovingImageType >  TransformInitializerType;
  TransformInitializerType::Pointer initializer
                                            = TransformInitializerType::New();
  initializer->SetTransform(   transform );
  initializer->SetFixedImage(  fixedImageReader->GetOutput() );
  initializer->SetMovingImage( movingImageReader->GetOutput() );
  initializer->MomentsOn();
  initializer->InitializeTransform();
  // Software Guide : EndCodeSnippet


  //  Software Guide : BeginLatex
  //
  //  Now we pass the transform object to the registration filter. It also will be updated as the
  //  ouput of the registration method since the "InPlace" is set.
  //
  //  Software Guide : EndLatex

  // Software Guide : BeginCodeSnippet
  registration->SetInitialTransform( transform );
  registration->InPlaceOn();
  // Software Guide : EndCodeSnippet


  //  Software Guide : BeginLatex
  //
  //  Keeping in mind that the scale of units in scaling, rotation and
  //  translation are quite different, we take advantage of the scaling
  //  functionality provided by the optimizers. We know that the first $N
  //  \times N$ elements of the parameters array correspond to the rotation
  //  matrix factor, and the last $N$ are the components of the translation to
  //  be applied after multiplication with the matrix is performed.
  //
  //  Software Guide : EndLatex


  double translationScale = 1.0 / 1000.0;

  if( argc > 8 )
    {
    translationScale = atof( argv[8] );
    }


  // Software Guide : BeginCodeSnippet
  typedef OptimizerType::ScalesType       OptimizerScalesType;
  OptimizerScalesType optimizerScales( transform->GetNumberOfParameters() );

  optimizerScales[0] =  1.0;
  optimizerScales[1] =  1.0;
  optimizerScales[2] =  1.0;
  optimizerScales[3] =  1.0;
  optimizerScales[4] =  translationScale;
  optimizerScales[5] =  translationScale;

  optimizer->SetScales( optimizerScales );
  // Software Guide : EndCodeSnippet


  //  Software Guide : BeginLatex
  //
  //  We also set the usual parameters of the optimization method. In this
  //  case we are using an
  //  \doxygen{RegularStepGradientDescentOptimizerv4}. Below, we define the
  //  optimization parameters like learning rate (initial step length), minimal
  //  step length and number of iterations. These last two act as stopping
  //  criteria for the optimization.
  //
  //  Software Guide : EndLatex

  double steplength = 1.0;

  if( argc > 6 )
    {
    steplength = atof( argv[6] );
    }


  unsigned int maxNumberOfIterations = 300;

  if( argc > 7 )
    {
    maxNumberOfIterations = atoi( argv[7] );
    }


  // Software Guide : BeginCodeSnippet
  optimizer->SetLearningRate( steplength );
  optimizer->SetMinimumStepLength( 0.0001 );
  optimizer->SetNumberOfIterations( maxNumberOfIterations );
  // Software Guide : EndCodeSnippet


  // Create the Command observer and register it with the optimizer.
  //
  CommandIterationUpdate::Pointer observer = CommandIterationUpdate::New();
  optimizer->AddObserver( itk::IterationEvent(), observer );


  // One level registration process without shrinking and smoothing.
  //
  const unsigned int numberOfLevels = 1;

  RegistrationType::ShrinkFactorsArrayType shrinkFactorsPerLevel;
  shrinkFactorsPerLevel.SetSize( 1 );
  shrinkFactorsPerLevel[0] = 1;

  RegistrationType::SmoothingSigmasArrayType smoothingSigmasPerLevel;
  smoothingSigmasPerLevel.SetSize( 1 );
  smoothingSigmasPerLevel[0] = 0;

  registration->SetNumberOfLevels ( numberOfLevels );
  registration->SetSmoothingSigmasPerLevel( smoothingSigmasPerLevel );
  registration->SetShrinkFactorsPerLevel( shrinkFactorsPerLevel );


  //  Software Guide : BeginLatex
  //
  //  Finally we trigger the execution of the registration method by calling
  //  the \code{Update()} method. The call is placed in a \code{try/catch}
  //  block in case any exceptions are thrown.
  //
  //  Software Guide : EndLatex

  // Software Guide : BeginCodeSnippet
  try
    {
    registration->Update();
    std::cout << "Optimizer stop condition: "
              << registration->GetOptimizer()->GetStopConditionDescription()
              << std::endl;
    }
  catch( itk::ExceptionObject & err )
    {
    std::cerr << "ExceptionObject caught !" << std::endl;
    std::cerr << err << std::endl;
    return EXIT_FAILURE;
    }
  // Software Guide : EndCodeSnippet


  //  Software Guide : BeginLatex
  //
  //  Once the optimization converges, we recover the parameters from the
  //  registration method. We can also recover the
  //  final value of the metric with the \code{GetValue()} method and the
  //  final number of iterations with the \code{GetCurrentIteration()}
  //  method.
  //
  //  \index{itk::RegistrationMethodv4!GetValue()}
  //  \index{itk::RegistrationMethodv4!GetCurrentIteration()}
  //
  //  Software Guide : EndLatex

  // Software Guide : BeginCodeSnippet
  const TransformType::ParametersType finalParameters =
                                  registration->GetOutput()->Get()->GetParameters();

  const double finalRotationCenterX = transform->GetCenter()[0];
  const double finalRotationCenterY = transform->GetCenter()[1];
  const double finalTranslationX    = finalParameters[4];
  const double finalTranslationY    = finalParameters[5];

  const unsigned int numberOfIterations = optimizer->GetCurrentIteration();
  const double bestValue = optimizer->GetValue();
  // Software Guide : EndCodeSnippet


  // Print out results
  //
  std::cout << "Result = " << std::endl;
  std::cout << " Center X      = " << finalRotationCenterX  << std::endl;
  std::cout << " Center Y      = " << finalRotationCenterY  << std::endl;
  std::cout << " Translation X = " << finalTranslationX  << std::endl;
  std::cout << " Translation Y = " << finalTranslationY  << std::endl;
  std::cout << " Iterations    = " << numberOfIterations << std::endl;
  std::cout << " Metric value  = " << bestValue          << std::endl;

  //Compute the rotation angle and scaling from SVD of the matrix
  // \todo Find a way to figure out if the scales are along X or along Y.
  // VNL returns the eigenvalues ordered from largest to smallest.

  vnl_matrix<double> p(2, 2);
  p[0][0] = (double) finalParameters[0];
  p[0][1] = (double) finalParameters[1];
  p[1][0] = (double) finalParameters[2];
  p[1][1] = (double) finalParameters[3];
  vnl_svd<double> svd(p);
  vnl_matrix<double> r(2, 2);
  r = svd.U() * vnl_transpose(svd.V());
  double angle = std::asin(r[1][0]);

  const double angleInDegrees = angle * 180.0 / vnl_math::pi;

  std::cout << " Scale 1         = " << svd.W(0)        << std::endl;
  std::cout << " Scale 2         = " << svd.W(1)        << std::endl;
  std::cout << " Angle (degrees) = " << angleInDegrees  << std::endl;


  //  Software Guide : BeginLatex
  //
  //  Let's execute this example over two of the images provided in
  //  \code{Examples/Data}:
  //
  //  \begin{itemize}
  //  \item \code{BrainProtonDensitySliceBorder20.png}
  //  \item \code{BrainProtonDensitySliceR10X13Y17.png}
  //  \end{itemize}
  //
  //  The second image is the result of intentionally rotating the first
  //  image by $10$ degrees and then translating by $(-13,-17)$.  Both images
  //  have unit-spacing and are shown in Figure
  //  \ref{fig:FixedMovingImageRegistration9}. We execute the code using the
  //  following parameters: step length=1.0, translation scale= 0.0001 and
  //  maximum number of iterations = 300. With these images and parameters
  //  the registration takes $92$ iterations and produces
  //
  //  \begin{center}
  //  \begin{verbatim}
  //   90   44.0851  [0.9849, -0.1729, 0.1725, 0.9848, 12.4541, 16.0759] AffineAngle: 9.9494
  //  \end{verbatim}
  //  \end{center}
  //
  //  These results are interpreted as
  //
  //  \begin{itemize}
  //  \item Iterations   = 92
  //  \item Final Metric = 44.0386
  //  \item Center       = $( 111.204,   131.591   )$ millimeters
  //  \item Translation  = $(   12.4542,  16.076 )$ millimeters
  //  \item Affine scales = $(1.00014, .999732)$
  //  \end{itemize}
  //
  //  The second component of the matrix values is usually associated with
  //  $\sin{\theta}$. We obtain the rotation through SVD of the affine
  //  matrix. The value is $9.9494$ degrees, which is approximately the
  //  intentional misalignment of $10.0$ degrees.
  //
  // \begin{figure}
  // \center
  // \includegraphics[width=0.44\textwidth]{BrainProtonDensitySliceBorder20}
  // \includegraphics[width=0.44\textwidth]{BrainProtonDensitySliceR10X13Y17}
  // \itkcaption[AffineTransform registration]{Fixed and moving images
  // provided as input to the registration method using the AffineTransform.}
  // \label{fig:FixedMovingImageRegistration9}
  // \end{figure}
  //
  //
  // \begin{figure}
  // \center
  // \includegraphics[width=0.32\textwidth]{ImageRegistration9Output}
  // \includegraphics[width=0.32\textwidth]{ImageRegistration9DifferenceBefore}
  // \includegraphics[width=0.32\textwidth]{ImageRegistration9DifferenceAfter}
  // \itkcaption[AffineTransform output images]{The resampled moving image
  // (left), and the difference between the fixed and moving images before (center)
  // and after (right) registration with the
  // AffineTransform transform.}
  // \label{fig:ImageRegistration9Outputs}
  // \end{figure}
  //
  // Figure \ref{fig:ImageRegistration9Outputs} shows the output of the
  // registration. The right most image of this figure shows the squared
  // magnitude difference between the fixed image and the resampled
  // moving image.
  //
  // \begin{figure}
  // \center
  // \includegraphics[height=0.32\textwidth]{ImageRegistration9TraceMetric}
  // \includegraphics[height=0.32\textwidth]{ImageRegistration9TraceAngle}
  // \includegraphics[height=0.32\textwidth]{ImageRegistration9TraceTranslations}
  // \itkcaption[AffineTransform output plots]{Metric values,
  // rotation angle and translations during the registration using the
  // AffineTransform transform.}
  // \label{fig:ImageRegistration9Plots}
  // \end{figure}
  //
  //  Figure \ref{fig:ImageRegistration9Plots} shows the plots of the main
  //  output parameters of the registration process. The metric values at every
  //  iteration are shown on the top plot. The angle values are shown on the bottom left plot,
  //  while the translation components of the registration are presented
  //  on the bottom right plot. Note that the final total offset of the transform
  //  is to be computed as a combination of the shift due rotation plus the
  //  explicit translation set on the transform.
  //
  //  Software Guide : EndLatex


  //  The following code is used to dump output images to files.
  //  They illustrate the final results of the registration.
  //  We will resample the moving image and write out the difference image
  //  before and after registration. We will also rescale the intensities of the
  //  difference images, so that they look better!
  typedef itk::ResampleImageFilter<
                            MovingImageType,
                            FixedImageType >    ResampleFilterType;

  ResampleFilterType::Pointer resampler = ResampleFilterType::New();

  resampler->SetTransform( transform );
  resampler->SetInput( movingImageReader->GetOutput() );

  FixedImageType::Pointer fixedImage = fixedImageReader->GetOutput();

  resampler->SetSize(    fixedImage->GetLargestPossibleRegion().GetSize() );
  resampler->SetOutputOrigin(  fixedImage->GetOrigin() );
  resampler->SetOutputSpacing( fixedImage->GetSpacing() );
  resampler->SetOutputDirection( fixedImage->GetDirection() );
  resampler->SetDefaultPixelValue( 100 );

  typedef  unsigned char  OutputPixelType;

  typedef itk::Image< OutputPixelType, Dimension > OutputImageType;

  typedef itk::CastImageFilter<
                        FixedImageType,
                        OutputImageType > CastFilterType;

  typedef itk::ImageFileWriter< OutputImageType >  WriterType;


  WriterType::Pointer      writer =  WriterType::New();
  CastFilterType::Pointer  caster =  CastFilterType::New();


  writer->SetFileName( argv[3] );


  caster->SetInput( resampler->GetOutput() );
  writer->SetInput( caster->GetOutput()   );
  writer->Update();


  typedef itk::SubtractImageFilter<
                                  FixedImageType,
                                  FixedImageType,
                                  FixedImageType > DifferenceFilterType;

  DifferenceFilterType::Pointer difference = DifferenceFilterType::New();

  difference->SetInput1( fixedImageReader->GetOutput() );
  difference->SetInput2( resampler->GetOutput() );

  WriterType::Pointer writer2 = WriterType::New();

  typedef itk::RescaleIntensityImageFilter<
                                  FixedImageType,
                                  OutputImageType >   RescalerType;

  RescalerType::Pointer intensityRescaler = RescalerType::New();

  intensityRescaler->SetInput( difference->GetOutput() );
  intensityRescaler->SetOutputMinimum(   0 );
  intensityRescaler->SetOutputMaximum( 255 );

  writer2->SetInput( intensityRescaler->GetOutput() );
  resampler->SetDefaultPixelValue( 1 );

  // Compute the difference image between the
  // fixed and resampled moving image.
  if( argc > 5 )
    {
    writer2->SetFileName( argv[5] );
    writer2->Update();
    }


  typedef itk::IdentityTransform< double, Dimension > IdentityTransformType;
  IdentityTransformType::Pointer identity = IdentityTransformType::New();

  // Compute the difference image between the
  // fixed and moving image before registration.
  if( argc > 4 )
    {
    resampler->SetTransform( identity );
    writer2->SetFileName( argv[4] );
    writer2->Update();
    }

  return EXIT_SUCCESS;
}