[Insight-users] # of spatial samples

[pinpress]

Hi,

I just found out that when I was using
MattesMutualInformationImageToImageMetric in registration, there is a
default number of spatial samples used in the Mutual Information evaluation,
which is 500. If I do not explicitly specify by calling:
SetNumberOfSpatialSamples, then the registration will not generally yield
good result.  Is this observation correct? I have only tested on one example
program so far.

The other question is: Exactly how these spatial samples were determined?
Are they all from the moving image? Are they randomly selected voxels from
the moving image? The reason I am asking is because I accidentally found out
that the number of spatial samples could be even larger than the total
number of voxels. How can this be possible? 

Thanks.
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