[Insight-users] large shearing deformation of soft tissue

[Tim Bhatnagar]

Hello all,

I am trying to quantify the amount of tissue deformation using "before and
after deformation" MR images (a series of 2D slices). However, there is a
significant amount of shearing in the deformation process which from what
I've read can be difficult to analyze. A previous colleague used a B-spline
deformable transform/registration algorithm in ITK and employed Mattes
Mutual Information, but his deformations were with much less (almost none)
shearing.

Is there anyone that could point me towards appropriate coding for this, or
suggest an alternative for measuring this deformation?

Many thanks.

-- 
Tim Bhatnagar
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