[Insight-users] large shearing deformation of soft tissue

[Dawood Masslawi]

Dear Tim,
The B-Spline deformable registration has an extensive capability when
it comes to compensating for nonlinear deformations. Using different 
settings can certainly improve the results, you can increase the number 
of grid nodes or use different optimization settings to gain better 
registration quality. However, if you won't use the B-Spline based 
registration other options are also available in ITK, like kernel 
transformation based registration, Finite Element based registration, 
Demons algorithm based registration, etc. You can find examples of 
these methods in the registration folder of the ITK's examples 
directory.
Best regards,
Dawood Almasslawi

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Hello all,

I am trying to quantify the amount of tissue deformation using "before and
after deformation" MR images (a series of 2D slices). However, there is a
significant amount of shearing in the deformation process which from what
I've read can be difficult to analyze. A previous colleague used a B-spline
deformable transform/registration algorithm in ITK and employed Mattes
Mutual Information, but his deformations were with much less (almost none)
shearing.

Is there anyone that could point me towards appropriate coding for this, or
suggest an alternative for measuring this deformation?

Many thanks.

-- 
Tim Bhatnagar


      
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