Ok missed something. if your working with 3D data and you want to extract 2D XY slices, you need to use start[2]=.... and size[2]=... . -- View this message in context: http://itk-insight-users.2283740.n2.nabble.com/extracting-slice-problem-tp7580104p7580114.html Sent from the ITK Insight Users mailing list archive at Nabble.com.