[ITK-users] What is an accepted duration of a 3D registration? Should I expect the MSE to "converge" to 0?

[Siavash Khallaghi]

Marina Bendersky wrote
> Hi Siavash,
> 
> Thanks again for your reply! I'm a newbie to both registration and ITK
> and I really value your help.
> 
> I would like to ask you about the 2 pre-processing points that you
> suggest to improve the registration:
> 
> 1- Would it be correct to normalize all images with the same filter
> (like NormalizeImageFilter), and then create the volumes and start the
> registration?
> 
> 2- You're right, there are probably local deformations and I've only
> been trying rigid/affine transforms. I'm comparing two volumes of
> different time points and there are likely to be transformations. I
> understood, however, that a deformable transformation might change the
> images (ie. the lesions), so I completely ruled deformable
> transformations out because my objective is to assess how the lesion
> changes over time ...
> 
> Is this correct? Or, should I still try a deformable registration?
> 
> In fact, my problem is the following: I have an image (in a fixed
> volume) with one or two points (annotated on a lesion) - I'm trying to
> identify the respective image in the moving volume (and the new
> location of the points).
> 
> Using the ITK outputs (matrix, translation, and center values), I
> computed the new coordinates of the points and I hoped that the new
> "z" value will determine the "correct" slice of the moving volume
> (time 2). Does this sound correct to you?
> 
> 
> Thanks so much!
> Marina





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