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	CMake is the cross-platform, open-source make system. CMake is used to control the software compilation process using simple platform and compiler independent configuration files. CMake generates native makefiles and workspaces that can be used in the compiler environment of your choice. CMake is quite sophisticated: it is possible to support complex environments requiring system configuration, pre-processor generation, code generation, and template instantiation.
	The Visualization ToolKit (VTK) is an open source, freely available software system for 3D computer graphics, image processing, and visualization used by thousands of researchers and developers around the world. VTK consists of a C++ class library, and several interpreted interface layers including Tcl/Tk, Java, and Python. Professional support and products for VTK are provided by Kitware, Inc. VTK supports a wide variety of visualization algorithms including scalar, vector, tensor, texture, and volumetric methods; and advanced modeling techniques such as implicit modelling, polygon reduction, mesh smoothing, cutting, contouring, and Delaunay triangulation. In addition, dozens of imaging algorithms have been directly integrated to allow the user to mix 2D imaging / 3D graphics algorithms and data.
	National Library of Medicine Insight Segmentation and Registration Toolkit (ITK) is an open-source software system to support the Visible Human Project. Currently under active development, ITK employs leading-edge segmentation and registration algorithms in two, three, and more dimensions.
	The National Alliance for Medical Imaging Computing (NAMIC) is a multi-institutional, interdisciplinary team of computer scientists, software engineers, and medical investigators who develop computational tools for the analysis and visualization of medical image data. The purpose of the center is to provide the infrastructure and environment for the development of computational algorithms and open source technologies, and then oversee the training and dissemination of these tools to the medical research community. This world-class software and development environment serves as a foundation for accelerating the development and deployment of computational tools that are readily accessible to the medical research community. The team combines cutting-edge computer vision research (to create medical imaging analysis algorithms) with state of the art software engineering techniques (based on "extreme" programming techniques in a distributed, open-source environment) to enable computational examination of both basic neurosience and neurological disorders. In developing this infrastructure resource, the team will significantly expand upon proven open systems technology and platforms.
	Parallel Visualization Application is an application designed with the need to visualize large data sets in mind. The goals of the ParaView project include developing an open-source, multi-platform visualization application that support distributed computation models to process large data sets. It has an open, flexible, and intuitive user interface and is develop an extensible architecture based on open standards. ParaView runs on distributed and shared memory parallel as well as single processor systems and has been succesfully tested on Windows, Linux and various Unix workstations and clusters. Under the hood, ParaView uses the Visualization Toolkit as the data processing and rendering engine and has a user interface written using a unique blend of Tcl/Tk and C++. Please go here for a detailed list of features.
	KWWidgets is a free, cross-platform and open-license GUI Toolkit. It provides low-level core widgets, advanced composite widgets, and high-level visualization-oriented widgets that can be interfaced to visualization libraries like VTK. KWWidgets is an object-oriented C++ toolkit that can interact and co-exist with Tcl/Tk directly from C++. It is wrapped automatically into a Tcl package, and therefore can be used directly from Tcl/Tk also, allowing for fast-prototyping and scripting.