[Insight-users] Anatomical Landmarks in MRI data

Luis Ibanez luis.ibanez at kitware.com
Thu Jul 26 17:56:58 EDT 2007

Hi Lars,

One option is to register a brain atlas to the image of the patient,
and to have pre-identified in the Atlas (maybe manually) the position
of all the landmarks that you need.

You could then use the Transform resulting from the image registration
to map the (manually identified) landmarks from the Atlas into the
coordinate system of the patient's image.

You will find information about image registration in ITK in the
ITK Software Guide:


As brain Atlas you could use the BrainWeb images or the Brain
Atlas of the SPL,... or actually any other brain image that you
may have at hand.



Lars Nygard wrote:
> Hi all,
> Im starting on this project where I have to extract characteristic
> anatomical landmarks in MRI data. Suitable candidates would
> be:
>     1. the nasion, defined as the most posterior midpoint of
>         the root of the nose.
>     2. The most posterior point of the rim of the posterior wall of the
>         external acoustic meatus
>     3. A point of the lateral canthus, defined as frontal to the orbital
>         margin of the zygomatic bone
> Maybe a bit difficult descpription but the goal is that you can point to
> these spots on the patient (lying on the operation table) with a optic 
> pointing device. Then the algorithm should find these points in order to
> do the registration of pre-operative MRI images to the operation table.
> Has anybody worked with this and what are the options availabe in ITK
> to find these (or other) characteristics points?
> thanks for any advice,
> regards,
> Lars Nygard
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