[Insight-users] preparing images for DeformableRegistration15

[Tim Bhatnagar]

Hello all,

I have two sets of Nifti-Analyze (*.hdr and disc image files)  images
(~48x48 pixels x 48 slices, 16-bit unsigned), of before and after an
applied tissue deformation. I segmented the tissue of interest from the
rest of the image data, and thresholded the images so only the tissue
pixels are non-zero. I have used DeformableRegistration15 to determine the
deformation field that transforms from undeformed->deformed states. The
registration runs well (I changed the '# of coarse b-spline grid nodes to
8, and the '# of fine b-spline grid nodes to 12', in hopes of being able to
accurately determine a large strain in a very localized region), but the
deformation field just looks off - most notably, the largest deformations
I'm seeing (using Paraview) occur in the zero-pixel (non-tissue) portions
of the field. All of the output image data from the algorithm has been
designed to be vtk files so I can use paraview.

Are there any key steps I'm missing here? I can give a further
description/data if needed, but I'm wondering if I've missed a basic point
somewhere along the way..

Thanks,

-- 
Tim Bhatnagar
PhD Candidate
Orthopaedic Injury Biomechanics Group
Department of Mechanical Engineering
University of British Columbia

Rm 5000 - 818 West 10th Ave.
Vancouver, BC
Canada
V5Z 1M9

Ph: (604) 675-8845
Fax: (604) 675-8820
Web: oibg.mech.ubc.ca
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