#include <itkTimeVaryingBSplineVelocityFieldImageRegistrationMethod.h>

Inheritance diagram for itk::TimeVaryingBSplineVelocityFieldImageRegistrationMethod< TFixedImage, TMovingImage, TOutputTransform >:

Collaboration diagram for itk::TimeVaryingBSplineVelocityFieldImageRegistrationMethod< TFixedImage, TMovingImage, TOutputTransform >:

Detailed Description

template<typename TFixedImage, typename TMovingImage, typename TOutputTransform = TimeVaryingBSplineVelocityFieldTransform<double, TFixedImage::ImageDimension>>
class itk::TimeVaryingBSplineVelocityFieldImageRegistrationMethod< TFixedImage, TMovingImage, TOutputTransform >

Interface method for the current registration framework using the time varying velocity field transform.

Output: The output is the updated transform which has been added to the composite transform.

This derived class from the SimpleImageRegistrationMethod class is specialized to handle time-varying velocity field transforms of which there are currently 2:

TimeVaryingDisplacementFieldTransform
GaussianSmoothingOnUpdateTimeVaryingDisplacementFieldTransform

The latter is derived from the former and performs an optional spatial and temporal smoothing on the update and total velocity fields. Integration of the velocity field is performed using 4th order Runge Kutta and is performed using the class itkTimeVaryingBSplineVelocityFieldIntegrationImageFilter.

Optimization occurs in an iterative fashion where for each sample time point, t, in the velocity field, we integrate the velocity field in the range [0, t] to yield the displacement field which warps fixed image to time point t. Simultaneously, we integrate the velocity field in the range [t, 1] to yield the displacement field transform which warps the moving image to time point t. The metric derivative for each time point of the velocity field calculated in this way produces the normalized update field (or gradient) of the velocity field to be added to the total field at each iteration after being multiplied by the learning rate and optionally smoothed. Mathematically, this can be described as

$v_{total} = G_1( v_{total} + \lambda * G_2( v_{update} ) )$

where

$ G_1 = $ gaussian smoothing on the total field $ G_2 = $ gaussian smoothing on the update field $\lambda =$ learning rate $v_{update} =$ the normalized velocity field where we normalize the velocity field at each time point separately by the max norm of the field at that time point. This is done due to a weakly necessary (but not sufficient) condition being that the velocity field have a constant norm for all time points.

Author: Nick Tustison; Brian Avants

Definition at line 93 of file itkTimeVaryingBSplineVelocityFieldImageRegistrationMethod.h.

Public Types
typedef Superclass::CompositeTransformType	CompositeTransformType

typedef SmartPointer< const Self >	ConstPointer

typedef DecoratedOutputTransformType::Pointer	DecoratedOutputTransformPointer

typedef Superclass::DecoratedOutputTransformType	DecoratedOutputTransformType

typedef OutputTransformType::DerivativeType	DerivativeType

typedef DerivativeType::ValueType	DerivativeValueType

typedef OutputTransformType::DisplacementFieldType	DisplacementFieldType

typedef TimeVaryingVelocityFieldControlPointLatticeType::PixelType	DisplacementVectorType

typedef FixedImageType::Pointer	FixedImagePointer

typedef TFixedImage	FixedImageType

typedef ImageMetricType::Pointer	ImageMetricPointer

typedef Superclass::ImageMetricType	ImageMetricType

typedef ImageMetricType::MeasureType	MeasureType

typedef MovingImageType::Pointer	MovingImagePointer

typedef TMovingImage	MovingImageType

typedef Superclass::MultiMetricType	MultiMetricType

typedef Array< SizeValueType >	NumberOfIterationsArrayType

typedef OutputTransformType::Pointer	OutputTransformPointer

typedef TOutputTransform	OutputTransformType

typedef SmartPointer< Self >	Pointer

typedef OutputTransformType::ScalarType	RealType

typedef TimeVaryingBSplineVelocityFieldImageRegistrationMethod	Self

typedef ImageRegistrationMethodv4 < TFixedImage, TMovingImage, TOutputTransform >	Superclass

typedef OutputTransformType::TimeVaryingVelocityFieldControlPointLatticePointer	TimeVaryingVelocityFieldControlPointLatticePointer

typedef OutputTransformType::TimeVaryingVelocityFieldControlPointLatticeType	TimeVaryingVelocityFieldControlPointLatticeType

typedef OutputTransformType::TimeVaryingVelocityFieldControlPointLatticePointer	TimeVaryingVelocityFieldPointer

typedef OutputTransformType::TimeVaryingVelocityFieldControlPointLatticeType	TimeVaryingVelocityFieldType

typedef ImageMetricType::VirtualImageType	VirtualImageType

Public Types inherited from itk::ImageRegistrationMethodv4< TFixedImage, TMovingImage, TOutputTransform >
typedef CompositeTransformType::Pointer	CompositeTransformPointer

typedef CompositeTransform < RealType, ImageDimension >	CompositeTransformType

typedef SmartPointer< const Self >	ConstPointer

typedef ProcessObject::DataObjectPointerArraySizeType	DataObjectPointerArraySizeType

typedef DecoratedOutputTransformType::Pointer	DecoratedOutputTransformPointer

typedef DataObjectDecorator < OutputTransformType >	DecoratedOutputTransformType

typedef OutputTransformType::DerivativeType	DerivativeType

typedef DerivativeType::ValueType	DerivativeValueType

typedef FixedImageType::Pointer	FixedImagePointer

typedef std::vector < FixedImagePointer >	FixedImagesContainerType

typedef TFixedImage	FixedImageType

typedef ImageToImageMetricv4 < FixedImageType, MovingImageType >	ImageMetricType

typedef InitialTransformType::Pointer	InitialTransformPointer

typedef Transform< RealType, ImageDimension, ImageDimension >	InitialTransformType

typedef MetricType::Pointer	MetricPointer

typedef ImageMetricType::FixedSampledPointSetType	MetricSamplePointSetType

typedef Array< RealType >	MetricSamplingPercentageArrayType

enum	MetricSamplingStrategyType { NONE, REGULAR, RANDOM }

typedef ObjectToObjectMetricBase	MetricType

typedef MovingImageType::Pointer	MovingImagePointer

typedef std::vector < MovingImagePointer >	MovingImagesContainerType

typedef TMovingImage	MovingImageType

typedef ObjectToObjectMultiMetricv4 < ImageDimension, ImageDimension >	MultiMetricType

typedef OptimizerType::Pointer	OptimizerPointer

typedef ObjectToObjectOptimizerBase	OptimizerType

typedef OutputTransformType::Pointer	OutputTransformPointer

typedef TOutputTransform	OutputTransformType

typedef SmartPointer< Self >	Pointer

typedef OutputTransformType::ScalarType	RealType

typedef ImageRegistrationMethodv4	Self

typedef Array< SizeValueType >	ShrinkFactorsArrayType

typedef Array< RealType >	SmoothingSigmasArrayType

typedef ProcessObject	Superclass

typedef TransformParametersAdaptorType::Pointer	TransformParametersAdaptorPointer

typedef std::vector < TransformParametersAdaptorPointer >	TransformParametersAdaptorsContainerType

typedef TransformParametersAdaptor < OutputTransformType >	TransformParametersAdaptorType

typedef ImageMetricType::VirtualImageType	VirtualImageType

Public Types inherited from itk::ProcessObject
typedef SmartPointer< const Self >	ConstPointer

typedef DataObject::DataObjectIdentifierType	DataObjectIdentifierType

typedef DataObject::Pointer	DataObjectPointer

typedef std::vector < DataObjectPointer >	DataObjectPointerArray

typedef DataObjectPointerArray::size_type	DataObjectPointerArraySizeType

typedef std::vector < DataObjectIdentifierType >	NameArray

typedef SmartPointer< Self >	Pointer

typedef ProcessObject	Self

typedef Object	Superclass

Public Types inherited from itk::Object
typedef SmartPointer< const Self >	ConstPointer

typedef SmartPointer< Self >	Pointer

typedef Object	Self

typedef LightObject	Superclass

Public Types inherited from itk::LightObject
typedef SmartPointer< const Self >	ConstPointer

typedef SmartPointer< Self >	Pointer

typedef LightObject	Self

Public Member Functions
virtual ::itk::LightObject::Pointer	CreateAnother (void) const

virtual const char *	GetNameOfClass () const


virtual void	SetLearningRate (RealType _arg)

virtual RealType	GetLearningRate () const


virtual void	SetNumberOfIterationsPerLevel (NumberOfIterationsArrayType _arg)

virtual NumberOfIterationsArrayType	GetNumberOfIterationsPerLevel () const


virtual void	SetConvergenceThreshold (RealType _arg)

virtual RealType	GetConvergenceThreshold () const


virtual void	SetConvergenceWindowSize (unsigned int _arg)

virtual unsigned int	GetConvergenceWindowSize () const


virtual void	SetNumberOfTimePointSamples (SizeValueType _arg)

virtual SizeValueType	GetNumberOfTimePointSamples () const

Public Member Functions inherited from itk::ImageRegistrationMethodv4< TFixedImage, TMovingImage, TOutputTransform >
virtual const RealType &	GetCurrentConvergenceValue ()

virtual const SizeValueType &	GetCurrentIteration ()

virtual SizeValueType	GetCurrentLevel () const

virtual const RealType &	GetCurrentMetricValue ()

virtual const bool &	GetIsConverged ()

virtual const DecoratedOutputTransformType *	GetOutput () const

virtual DataObjectPointer	MakeOutput (DataObjectPointerArraySizeType)

void	SetMetricSamplingPercentage (const RealType)

virtual void	SetFixedImage (const FixedImageType *image)

virtual const FixedImageType *	GetFixedImage () const

virtual void	SetFixedImage (SizeValueType, const FixedImageType *)

virtual const FixedImageType *	GetFixedImage (SizeValueType) const

virtual void	SetMovingImage (const MovingImageType *image)

virtual const MovingImageType *	GetMovingImage () const

virtual void	SetMovingImage (SizeValueType, const MovingImageType *)

virtual const MovingImageType *	GetMovingImage (SizeValueType) const

virtual void	SetOptimizer (OptimizerType *_arg)

virtual OptimizerType *	GetOptimizer ()

virtual void	SetMetric (MetricType *_arg)

virtual MetricType *	GetMetric ()

virtual void	SetMetricSamplingStrategy (MetricSamplingStrategyType _arg)

virtual MetricSamplingStrategyType	GetMetricSamplingStrategy () const

virtual void	SetMetricSamplingPercentagePerLevel (MetricSamplingPercentageArrayType _arg)

virtual MetricSamplingPercentageArrayType	GetMetricSamplingPercentagePerLevel () const

virtual void	SetFixedInitialTransform (InitialTransformType *_arg)

virtual const InitialTransformType *	GetFixedInitialTransform ()

virtual void	SetMovingInitialTransform (InitialTransformType *_arg)

virtual const InitialTransformType *	GetMovingInitialTransform ()

void	SetTransformParametersAdaptorsPerLevel (TransformParametersAdaptorsContainerType &)

const TransformParametersAdaptorsContainerType &	GetTransformParametersAdaptorsPerLevel () const

void	SetNumberOfLevels (const SizeValueType)

virtual SizeValueType	GetNumberOfLevels () const

virtual void	SetShrinkFactorsPerLevel (ShrinkFactorsArrayType _arg)

virtual ShrinkFactorsArrayType	GetShrinkFactorsPerLevel () const

virtual void	SetSmoothingSigmasPerLevel (SmoothingSigmasArrayType _arg)

virtual SmoothingSigmasArrayType	GetSmoothingSigmasPerLevel () const

virtual void	SetSmoothingSigmasAreSpecifiedInPhysicalUnits (bool _arg)

virtual bool	GetSmoothingSigmasAreSpecifiedInPhysicalUnits () const

virtual void	SmoothingSigmasAreSpecifiedInPhysicalUnitsOn ()

virtual void	SmoothingSigmasAreSpecifiedInPhysicalUnitsOff ()

Public Member Functions inherited from itk::ProcessObject
virtual void	AbortGenerateDataOff ()

virtual void	AbortGenerateDataOn ()

virtual void	EnlargeOutputRequestedRegion (DataObject *)

virtual const bool &	GetAbortGenerateData ()

NameArray	GetInputNames () const

MultiThreader *	GetMultiThreader () const

DataObjectPointerArraySizeType	GetNumberOfIndexedInputs () const

DataObjectPointerArraySizeType	GetNumberOfInputs () const

DataObjectPointerArraySizeType	GetNumberOfOutputs () const

virtual DataObjectPointerArraySizeType	GetNumberOfValidRequiredInputs () const

NameArray	GetOutputNames () const

virtual const float &	GetProgress ()

NameArray	GetRequiredInputNames () const

bool	HasInput (const DataObjectIdentifierType &key) const

bool	HasOutput (const DataObjectIdentifierType &key) const

virtual DataObjectPointer	MakeOutput (const DataObjectIdentifierType &)

virtual void	PrepareOutputs ()

virtual void	PropagateRequestedRegion (DataObject *output)

virtual void	ResetPipeline ()

virtual void	SetAbortGenerateData (bool _arg)

virtual void	SetProgress (float _arg)

virtual void	Update ()

virtual void	UpdateLargestPossibleRegion ()

virtual void	UpdateOutputData (DataObject *output)

virtual void	UpdateOutputInformation ()

void	UpdateProgress (float amount)

DataObjectPointerArray	GetInputs ()

DataObjectPointerArray	GetOutputs ()

DataObjectPointerArray	GetIndexedInputs ()

DataObjectPointerArray	GetIndexedOutputs ()

DataObjectPointerArraySizeType	GetNumberOfIndexedOutputs () const

virtual void	SetReleaseDataFlag (bool flag)

virtual bool	GetReleaseDataFlag () const

void	ReleaseDataFlagOn ()

void	ReleaseDataFlagOff ()

virtual void	SetReleaseDataBeforeUpdateFlag (bool _arg)

virtual const bool &	GetReleaseDataBeforeUpdateFlag ()

virtual void	ReleaseDataBeforeUpdateFlagOn ()

virtual void	ReleaseDataBeforeUpdateFlagOff ()

virtual void	SetNumberOfThreads (ThreadIdType _arg)

virtual const ThreadIdType &	GetNumberOfThreads ()

Public Member Functions inherited from itk::Object
unsigned long	AddObserver (const EventObject &event, Command *)

unsigned long	AddObserver (const EventObject &event, Command *) const

virtual void	DebugOff () const

virtual void	DebugOn () const

Command *	GetCommand (unsigned long tag)

bool	GetDebug () const

MetaDataDictionary &	GetMetaDataDictionary (void)

const MetaDataDictionary &	GetMetaDataDictionary (void) const

virtual ModifiedTimeType	GetMTime () const

virtual const TimeStamp &	GetTimeStamp () const

bool	HasObserver (const EventObject &event) const

void	InvokeEvent (const EventObject &)

void	InvokeEvent (const EventObject &) const

virtual void	Modified () const

virtual void	Register () const

void	RemoveAllObservers ()

void	RemoveObserver (unsigned long tag)

void	SetDebug (bool debugFlag) const

void	SetMetaDataDictionary (const MetaDataDictionary &rhs)

virtual void	SetReferenceCount (int)

virtual void	UnRegister () const

Public Member Functions inherited from itk::LightObject
virtual void	Delete ()

virtual int	GetReferenceCount () const

	itkCloneMacro (Self)

void	Print (std::ostream &os, Indent indent=0) const

Static Public Member Functions
static Pointer	New ()

Static Public Member Functions inherited from itk::ImageRegistrationMethodv4< TFixedImage, TMovingImage, TOutputTransform >
static Pointer	New ()

Static Public Attributes
static const unsigned int	ImageDimension = TFixedImage::ImageDimension

Static Public Attributes inherited from itk::ImageRegistrationMethodv4< TFixedImage, TMovingImage, TOutputTransform >
static const unsigned int	ImageDimension = TFixedImage::ImageDimension

Protected Member Functions
virtual void	GenerateData ()

virtual void	PrintSelf (std::ostream &os, Indent indent) const

virtual void	StartOptimization ()

	TimeVaryingBSplineVelocityFieldImageRegistrationMethod ()

virtual	~TimeVaryingBSplineVelocityFieldImageRegistrationMethod ()

Protected Member Functions inherited from itk::ImageRegistrationMethodv4< TFixedImage, TMovingImage, TOutputTransform >
	ImageRegistrationMethodv4 ()

virtual void	InitializeRegistrationAtEachLevel (const SizeValueType)

virtual void	SetMetricSamplePoints ()

virtual	~ImageRegistrationMethodv4 ()

Protected Member Functions inherited from itk::ProcessObject
virtual void	AddInput (DataObject *input)

virtual void	AddOutput (DataObject *output)

bool	AddRequiredInputName (const DataObjectIdentifierType &)

virtual void	CacheInputReleaseDataFlags ()

virtual void	GenerateInputRequestedRegion ()

virtual void	GenerateOutputInformation ()

virtual void	GenerateOutputRequestedRegion (DataObject *output)

virtual const DataObjectPointerArraySizeType &	GetNumberOfRequiredOutputs ()

bool	IsIndexedInputName (const DataObjectIdentifierType &) const

bool	IsIndexedOutputName (const DataObjectIdentifierType &) const

bool	IsRequiredInputName (const DataObjectIdentifierType &) const

	itkLegacyMacro (virtual void RemoveInput(DataObject *input))

	itkLegacyMacro (virtual void RemoveOutput(DataObject *output))

	itkLegacyMacro (void SetNumberOfInputs(DataObjectPointerArraySizeType num))

	itkLegacyMacro (void SetNumberOfOutputs(DataObjectPointerArraySizeType num))

DataObjectPointerArraySizeType	MakeIndexFromInputName (const DataObjectIdentifierType &name) const

DataObjectPointerArraySizeType	MakeIndexFromOutputName (const DataObjectIdentifierType &name) const

DataObjectIdentifierType	MakeNameFromInputIndex (DataObjectPointerArraySizeType idx) const

DataObjectIdentifierType	MakeNameFromOutputIndex (DataObjectPointerArraySizeType idx) const

	ProcessObject ()

virtual void	PropagateResetPipeline ()

virtual void	ReleaseInputs ()

virtual void	RemoveInput (const DataObjectIdentifierType &key)

virtual void	RemoveInput (DataObjectPointerArraySizeType)

virtual void	RemoveOutput (const DataObjectIdentifierType &key)

virtual void	RemoveOutput (DataObjectPointerArraySizeType idx)

bool	RemoveRequiredInputName (const DataObjectIdentifierType &)

virtual void	RestoreInputReleaseDataFlags ()

virtual void	SetInput (const DataObjectIdentifierType &key, DataObject *input)

virtual void	SetNthInput (DataObjectPointerArraySizeType num, DataObject *input)

virtual void	SetNthOutput (DataObjectPointerArraySizeType num, DataObject *output)

void	SetNumberOfIndexedInputs (DataObjectPointerArraySizeType num)

void	SetNumberOfIndexedOutputs (DataObjectPointerArraySizeType num)

virtual void	SetNumberOfRequiredOutputs (DataObjectPointerArraySizeType _arg)

virtual void	SetOutput (const DataObjectIdentifierType &key, DataObject *output)

virtual void	SetPrimaryInput (DataObject *input)

virtual void	SetPrimaryOutput (DataObject *output)

void	SetRequiredInputNames (const NameArray &)

virtual void	VerifyInputInformation ()

virtual void	VerifyPreconditions ()

	~ProcessObject ()

DataObject *	GetInput (const DataObjectIdentifierType &key)

const DataObject *	GetInput (const DataObjectIdentifierType &key) const

DataObject *	GetInput (DataObjectPointerArraySizeType)

const DataObject *	GetInput (DataObjectPointerArraySizeType idx) const

DataObject *	GetPrimaryInput ()

const DataObject *	GetPrimaryInput () const

virtual void	SetPrimaryInputName (const DataObjectIdentifierType &key)

virtual const char *	GetPrimaryInputName () const

DataObject *	GetOutput (const DataObjectIdentifierType &key)

const DataObject *	GetOutput (const DataObjectIdentifierType &key) const

virtual void	SetPrimaryOutputName (const DataObjectIdentifierType &key)

virtual const char *	GetPrimaryOutputName () const

DataObject *	GetOutput (DataObjectPointerArraySizeType idx)

const DataObject *	GetOutput (DataObjectPointerArraySizeType idx) const

DataObject *	GetPrimaryOutput ()

const DataObject *	GetPrimaryOutput () const

virtual void	SetNumberOfRequiredInputs (DataObjectPointerArraySizeType)

virtual const DataObjectPointerArraySizeType &	GetNumberOfRequiredInputs ()

virtual void	PushBackInput (const DataObject *input)

virtual void	PopBackInput ()

virtual void	PushFrontInput (const DataObject *input)

virtual void	PopFrontInput ()

Protected Member Functions inherited from itk::Object
	Object ()

bool	PrintObservers (std::ostream &os, Indent indent) const

virtual void	SetTimeStamp (const TimeStamp &time)

virtual	~Object ()

Protected Member Functions inherited from itk::LightObject
virtual LightObject::Pointer	InternalClone () const

	LightObject ()

virtual void	PrintHeader (std::ostream &os, Indent indent) const

virtual void	PrintTrailer (std::ostream &os, Indent indent) const

virtual	~LightObject ()

Private Member Functions
void	operator= (const Self &)

	TimeVaryingBSplineVelocityFieldImageRegistrationMethod (const Self &)

Private Attributes
RealType	m_ConvergenceThreshold

unsigned int	m_ConvergenceWindowSize

RealType	m_LearningRate

NumberOfIterationsArrayType	m_NumberOfIterationsPerLevel

SizeValueType	m_NumberOfTimePointSamples

Additional Inherited Members
Protected Types inherited from itk::LightObject
typedef int	InternalReferenceCountType

Protected Attributes inherited from itk::ImageRegistrationMethodv4< TFixedImage, TMovingImage, TOutputTransform >
CompositeTransformPointer	m_CompositeTransform

RealType	m_CurrentConvergenceValue

SizeValueType	m_CurrentIteration

SizeValueType	m_CurrentLevel

RealType	m_CurrentMetricValue

InitialTransformPointer	m_FixedInitialTransform

FixedImagesContainerType	m_FixedSmoothImages

bool	m_IsConverged

MetricPointer	m_Metric

MetricSamplingPercentageArrayType	m_MetricSamplingPercentagePerLevel

MetricSamplingStrategyType	m_MetricSamplingStrategy

InitialTransformPointer	m_MovingInitialTransform

MovingImagesContainerType	m_MovingSmoothImages

SizeValueType	m_NumberOfFixedImages

SizeValueType	m_NumberOfLevels

SizeValueType	m_NumberOfMovingImages

OptimizerPointer	m_Optimizer

OutputTransformPointer	m_OutputTransform

ShrinkFactorsArrayType	m_ShrinkFactorsPerLevel

bool	m_SmoothingSigmasAreSpecifiedInPhysicalUnits

SmoothingSigmasArrayType	m_SmoothingSigmasPerLevel

TransformParametersAdaptorsContainerType	m_TransformParametersAdaptorsPerLevel