#include <itkSyNImageRegistrationMethod.h>

Inheritance diagram for itk::SyNImageRegistrationMethod< TFixedImage, TMovingImage, TOutputTransform, TVirtualImage, TPointSet >:

Collaboration diagram for itk::SyNImageRegistrationMethod< TFixedImage, TMovingImage, TOutputTransform, TVirtualImage, TPointSet >:

Detailed Description

template<typename TFixedImage, typename TMovingImage, typename TOutputTransform = DisplacementFieldTransform<double, TFixedImage::ImageDimension>, typename TVirtualImage = TFixedImage, typename TPointSet = PointSet<unsigned int, TFixedImage::ImageDimension>>
class itk::SyNImageRegistrationMethod< TFixedImage, TMovingImage, TOutputTransform, TVirtualImage, TPointSet >

Interface method for the performing greedy SyN image registration.

For greedy SyN we use m_Transform to map the time-parameterized middle image to the fixed image (and vice versa using m_Transform->GetInverseDisplacementField() ). We employ another ivar, m_InverseTransform, to map the time-parameterized middle image to the moving image.

Output: The output is the updated transform which has been added to the composite transform.

This implementation is based on the source code in Advanced Normalization Tools (ANTs)

Avants, B. B.; Tustison, N. J.; Song, G.; Cook, P. A.; Klein, A. & Gee, J. C. A reproducible evaluation of ANTs similarity metric performance in brain image registration. Neuroimage, Penn Image Computing and Science Laboratory, University of Pennsylvania, 2011, 54, 2033-2044

The original paper discussing the method is here:

Avants, B. B.; Epstein, C. L.; Grossman, M. & Gee, J. C. Symmetric diffeomorphic image registration with cross-correlation: evaluating automated labeling of elderly and neurodegenerative brain. Med Image Anal, Department of Radiology, University of Pennsylvania, 2008, 12, 26-41

The method evolved since that time with crucial contributions from Gang Song and Nick Tustison. Though similar in spirit, this implementation is not identical.

Todo:: Need to allow the fixed image to have a composite transform.

Author: Nick Tustison; Brian Avants

Definition at line 70 of file itkSyNImageRegistrationMethod.h.

Public Types
using	CompositeTransformType = typename Superclass::CompositeTransformType

using	ConstPointer = SmartPointer< const Self >

using	DecoratedOutputTransformPointer = typename DecoratedOutputTransformType::Pointer

using	DecoratedOutputTransformType = typename Superclass::DecoratedOutputTransformType

using	DerivativeType = typename OutputTransformType::DerivativeType

using	DerivativeValueType = typename DerivativeType::ValueType

using	DisplacementFieldPointer = typename DisplacementFieldType::Pointer

using	DisplacementFieldTransformPointer = typename DisplacementFieldTransformType::Pointer

using	DisplacementFieldTransformType = DisplacementFieldTransform< RealType, ImageDimension >

using	DisplacementFieldType = typename OutputTransformType::DisplacementFieldType

using	DisplacementVectorType = typename DisplacementFieldType::PixelType

using	FixedImageMasksContainerType = typename Superclass::FixedImageMasksContainerType

using	FixedImageMaskType = typename Superclass::FixedImageMaskType

using	FixedImagePointer = typename FixedImageType::Pointer

using	FixedImagesContainerType = typename Superclass::FixedImagesContainerType

using	FixedImageType = TFixedImage

using	FixedMaskImageType = typename ImageMaskSpatialObjectType::ImageType

using	ImageMaskSpatialObjectType = ImageMaskSpatialObject< ImageDimension >

using	ImageMetricPointer = typename ImageMetricType::Pointer

using	ImageMetricType = typename Superclass::ImageMetricType

using	InitialTransformType = typename Superclass::InitialTransformType

using	MeasureType = typename ImageMetricType::MeasureType

using	MetricPointer = typename MetricType::Pointer

using	MetricType = typename Superclass::MetricType

using	MovingImageMasksContainerType = typename Superclass::MovingImageMasksContainerType

using	MovingImageMaskType = typename Superclass::MovingImageMaskType

using	MovingImagePointer = typename MovingImageType::Pointer

using	MovingImagesContainerType = typename Superclass::MovingImagesContainerType

using	MovingImageType = TMovingImage

using	MovingMaskImageType = typename ImageMaskSpatialObjectType::ImageType

using	MultiMetricType = typename Superclass::MultiMetricType

using	NumberOfIterationsArrayType = Array< SizeValueType >

using	OutputTransformPointer = typename OutputTransformType::Pointer

using	OutputTransformType = TOutputTransform

using	Pointer = SmartPointer< Self >

using	PointSetMetricType = typename Superclass::PointSetMetricType

using	PointSetPointer = typename PointSetType::Pointer

using	PointSetsContainerType = typename Superclass::PointSetsContainerType

using	PointSetType = typename Superclass::PointSetType

using	RealType = typename OutputTransformType::ScalarType

using	Self = SyNImageRegistrationMethod

using	Superclass = ImageRegistrationMethodv4< TFixedImage, TMovingImage, TOutputTransform, TVirtualImage, TPointSet >

using	TransformBaseType = typename CompositeTransformType::TransformType

using	VirtualImageBaseConstPointer = typename Superclass::VirtualImageBaseConstPointer

using	VirtualImageBaseType = typename Superclass::VirtualImageBaseType

using	VirtualImageType = typename Superclass::VirtualImageType

Public Types inherited from itk::ImageRegistrationMethodv4< TFixedImage, TMovingImage, TOutputTransform, TVirtualImage, TPointSet >
using	CompositeTransformPointer = typename CompositeTransformType::Pointer

using	CompositeTransformType = CompositeTransform< RealType, ImageDimension >

using	ConstPointer = SmartPointer< const Self >

using	DataObjectPointerArraySizeType = ProcessObject::DataObjectPointerArraySizeType

using	DecoratedInitialTransformPointer = typename DecoratedInitialTransformType::Pointer

using	DecoratedInitialTransformType = DataObjectDecorator< InitialTransformType >

using	DecoratedOutputTransformPointer = typename DecoratedOutputTransformType::Pointer

using	DecoratedOutputTransformType = DataObjectDecorator< OutputTransformType >

using	DerivativeType = typename OutputTransformType::DerivativeType

using	DerivativeValueType = typename DerivativeType::ValueType

using	FixedImageConstPointer = typename FixedImageType::ConstPointer

using	FixedImageMaskConstPointer = typename FixedImageMaskType::ConstPointer

using	FixedImageMasksContainerType = std::vector< FixedImageMaskConstPointer >

using	FixedImageMaskType = typename ImageMetricType::FixedImageMaskType

using	FixedImagePointer = typename FixedImageType::Pointer

using	FixedImagesContainerType = std::vector< FixedImageConstPointer >

using	FixedImageType = TFixedImage

using	ImageMetricType = ImageToImageMetricv4< FixedImageType, MovingImageType, VirtualImageType, RealType >

using	InitialTransformPointer = typename InitialTransformType::Pointer

using	InitialTransformType = Transform< RealType, ImageDimension, ImageDimension >

using	MetricPointer = typename MetricType::Pointer

using	MetricSamplePointSetType = typename ImageMetricType::FixedSampledPointSetType

using	MetricSamplingPercentageArrayType = Array< RealType >

enum	MetricSamplingStrategyType { NONE, REGULAR, RANDOM }

using	MetricType = ObjectToObjectMetricBaseTemplate< RealType >

using	MovingImageConstPointer = typename MovingImageType::ConstPointer

using	MovingImageMaskConstPointer = typename MovingImageMaskType::ConstPointer

using	MovingImageMasksContainerType = std::vector< MovingImageMaskConstPointer >

using	MovingImageMaskType = typename ImageMetricType::MovingImageMaskType

using	MovingImagePointer = typename MovingImageType::Pointer

using	MovingImagesContainerType = std::vector< MovingImageConstPointer >

using	MovingImageType = TMovingImage

using	MultiMetricType = ObjectToObjectMultiMetricv4< ImageDimension, ImageDimension, VirtualImageType, RealType >

using	OptimizerPointer = typename OptimizerType::Pointer

using	OptimizerType = ObjectToObjectOptimizerBaseTemplate< RealType >

using	OptimizerWeightsType = typename OptimizerType::ScalesType

using	OutputTransformPointer = typename OutputTransformType::Pointer

using	OutputTransformType = TOutputTransform

using	Pointer = SmartPointer< Self >

using	PointSetConstPointer = typename PointSetType::ConstPointer

using	PointSetMetricType = PointSetToPointSetMetricv4< PointSetType, PointSetType, RealType >

using	PointSetsContainerType = std::vector< PointSetConstPointer >

using	PointSetType = TPointSet

using	RealType = typename OutputTransformType::ScalarType

using	Self = ImageRegistrationMethodv4

using	ShrinkFactorsArrayType = Array< SizeValueType >

using	ShrinkFactorsPerDimensionContainerType = typename ShrinkFilterType::ShrinkFactorsType

using	ShrinkFilterType = ShrinkImageFilter< FixedImageType, VirtualImageType >

using	SmoothingSigmasArrayType = Array< RealType >

using	Superclass = ProcessObject

using	TransformParametersAdaptorPointer = typename TransformParametersAdaptorType::Pointer

using	TransformParametersAdaptorsContainerType = std::vector< TransformParametersAdaptorPointer >

using	TransformParametersAdaptorType = TransformParametersAdaptorBase< InitialTransformType >

using	VectorType = Vector< RealType, ImageDimension >

using	VirtualImageBaseConstPointer = typename VirtualImageBaseType::ConstPointer

using	VirtualImageBaseType = ImageBase< ImageDimension >

using	VirtualImagePointer = typename VirtualImageType::Pointer

using	VirtualImageType = TVirtualImage

Public Types inherited from itk::ProcessObject
using	ConstPointer = SmartPointer< const Self >

using	DataObjectIdentifierType = DataObject::DataObjectIdentifierType

using	DataObjectPointer = DataObject::Pointer

using	DataObjectPointerArray = std::vector< DataObjectPointer >

using	DataObjectPointerArraySizeType = DataObjectPointerArray::size_type

using	MultiThreaderType = MultiThreaderBase

using	NameArray = std::vector< DataObjectIdentifierType >

using	Pointer = SmartPointer< Self >

using	Self = ProcessObject

using	Superclass = Object

Public Types inherited from itk::Object
using	ConstPointer = SmartPointer< const Self >

using	Pointer = SmartPointer< Self >

using	Self = Object

using	Superclass = LightObject

Public Types inherited from itk::LightObject
using	ConstPointer = SmartPointer< const Self >

using	Pointer = SmartPointer< Self >

using	Self = LightObject

Public Member Functions
virtual ::itk::LightObject::Pointer	CreateAnother () const

virtual const char *	GetNameOfClass () const


virtual void	SetLearningRate (RealType _arg)

virtual RealType	GetLearningRate () const


virtual void	SetNumberOfIterationsPerLevel (NumberOfIterationsArrayType _arg)

virtual NumberOfIterationsArrayType	GetNumberOfIterationsPerLevel () const


virtual void	SetConvergenceThreshold (RealType _arg)

virtual RealType	GetConvergenceThreshold () const


virtual void	SetConvergenceWindowSize (unsigned int _arg)

virtual unsigned int	GetConvergenceWindowSize () const


virtual void	SetDownsampleImagesForMetricDerivatives (bool _arg)

virtual bool	GetDownsampleImagesForMetricDerivatives () const


virtual void	SetAverageMidPointGradients (bool _arg)

virtual bool	GetAverageMidPointGradients () const


virtual void	SetGaussianSmoothingVarianceForTheUpdateField (RealType _arg)

virtual const RealType &	GetGaussianSmoothingVarianceForTheUpdateField () const


virtual void	SetGaussianSmoothingVarianceForTheTotalField (RealType _arg)

virtual const RealType &	GetGaussianSmoothingVarianceForTheTotalField () const


virtual OutputTransformType *	GetModifiableFixedToMiddleTransform ()

virtual const OutputTransformType *	GetFixedToMiddleTransform () const

virtual OutputTransformType *	GetModifiableMovingToMiddleTransform ()

virtual const OutputTransformType *	GetMovingToMiddleTransform () const


virtual void	SetFixedToMiddleTransform (OutputTransformType *_arg)

virtual void	SetMovingToMiddleTransform (OutputTransformType *_arg)

Public Member Functions inherited from itk::ImageRegistrationMethodv4< TFixedImage, TMovingImage, TOutputTransform, TVirtualImage, TPointSet >
virtual const RealType &	GetCurrentConvergenceValue () const

virtual const SizeValueType &	GetCurrentIteration () const

virtual SizeValueType	GetCurrentLevel () const

virtual const RealType &	GetCurrentMetricValue () const

virtual const InitialTransformType *	GetFixedInitialTransform () const

virtual const DataObjectDecorator < InitialTransformType > *	GetFixedInitialTransformInput () const

virtual const DataObjectDecorator < InitialTransformType > *	GetFixedInitialTransformInput () const

virtual const InitialTransformType *	GetInitialTransform () const

virtual const DataObjectDecorator < InitialTransformType > *	GetInitialTransformInput () const

virtual const DataObjectDecorator < InitialTransformType > *	GetInitialTransformInput () const

virtual const DataObjectDecorator < InitialTransformType > *	GetInputnumber () const

virtual const DataObjectDecorator < InitialTransformType > *	GetInputnumber () const

virtual const DataObjectDecorator < InitialTransformType > *	GetInputnumber () const

virtual const bool &	GetIsConverged () const

virtual OutputTransformType *	GetModifiableTransform ()

virtual const InitialTransformType *	GetMovingInitialTransform () const

virtual const DataObjectDecorator < InitialTransformType > *	GetMovingInitialTransformInput () const

virtual const DataObjectDecorator < InitialTransformType > *	GetMovingInitialTransformInput () const

virtual const OutputTransformType *	GetTransform () const

virtual DecoratedOutputTransformType *	GetTransformOutput ()

virtual const DecoratedOutputTransformType *	GetTransformOutput () const

void	InitializeCenterOfLinearOutputTransform ()

DataObjectPointer	MakeOutput (DataObjectPointerArraySizeType) override

virtual void	SetFixedInitialTransform (const InitialTransformType *_arg)

virtual void	SetFixedInitialTransformInput (const DataObjectDecorator< InitialTransformType > *_arg)

virtual void	SetInitialTransform (const InitialTransformType *_arg)

virtual void	SetInitialTransformInput (const DataObjectDecorator< InitialTransformType > *_arg)

virtual void	SetInputnumber (const DataObjectDecorator< InitialTransformType > *_arg)

virtual void	SetInputnumber (const DataObjectDecorator< InitialTransformType > *_arg)

virtual void	SetInputnumber (const DataObjectDecorator< InitialTransformType > *_arg)

void	SetMetricSamplingPercentage (const RealType)

virtual void	SetMovingInitialTransform (const InitialTransformType *_arg)

virtual void	SetMovingInitialTransformInput (const DataObjectDecorator< InitialTransformType > *_arg)

virtual void	SetFixedImage (const FixedImageType *image)

virtual const FixedImageType *	GetFixedImage () const

virtual void	SetFixedImage (SizeValueType, const FixedImageType *)

virtual const FixedImageType *	GetFixedImage (SizeValueType) const

virtual void	SetMovingImage (const MovingImageType *image)

virtual const MovingImageType *	GetMovingImage () const

virtual void	SetMovingImage (SizeValueType, const MovingImageType *)

virtual const MovingImageType *	GetMovingImage (SizeValueType) const

virtual void	SetFixedPointSet (const PointSetType *pointSet)

virtual const PointSetType *	GetFixedPointSet () const

virtual void	SetFixedPointSet (SizeValueType, const PointSetType *)

virtual const PointSetType *	GetFixedPointSet (SizeValueType) const

virtual void	SetMovingPointSet (const PointSetType *pointSet)

virtual const PointSetType *	GetMovingPointSet () const

virtual void	SetMovingPointSet (SizeValueType, const PointSetType *)

virtual const PointSetType *	GetMovingPointSet (SizeValueType) const

virtual void	SetOptimizer (OptimizerType *_arg)

virtual OptimizerType *	GetModifiableOptimizer ()

virtual const OptimizerType *	GetOptimizer () const

void	SetOptimizerWeights (OptimizerWeightsType &)

virtual OptimizerWeightsType	GetOptimizerWeights () const

virtual void	SetMetric (MetricType *_arg)

virtual MetricType *	GetModifiableMetric ()

virtual const MetricType *	GetMetric () const

virtual void	SetMetricSamplingStrategy (MetricSamplingStrategyType _arg)

virtual MetricSamplingStrategyType	GetMetricSamplingStrategy () const

void	MetricSamplingReinitializeSeed ()

void	MetricSamplingReinitializeSeed (int seed)

virtual void	SetMetricSamplingPercentagePerLevel (const MetricSamplingPercentageArrayType &samplingPercentages)

virtual MetricSamplingPercentageArrayType	GetMetricSamplingPercentagePerLevel () const

void	SetTransformParametersAdaptorsPerLevel (TransformParametersAdaptorsContainerType &)

const TransformParametersAdaptorsContainerType &	GetTransformParametersAdaptorsPerLevel () const

void	SetNumberOfLevels (const SizeValueType)

virtual SizeValueType	GetNumberOfLevels () const

void	SetShrinkFactorsPerLevel (ShrinkFactorsArrayType factors)

ShrinkFactorsPerDimensionContainerType	GetShrinkFactorsPerDimension (const unsigned int level) const

void	SetShrinkFactorsPerDimension (unsigned int level, ShrinkFactorsPerDimensionContainerType factors)

virtual void	SetSmoothingSigmasPerLevel (SmoothingSigmasArrayType _arg)

virtual SmoothingSigmasArrayType	GetSmoothingSigmasPerLevel () const

virtual void	SetSmoothingSigmasAreSpecifiedInPhysicalUnits (bool _arg)

virtual bool	GetSmoothingSigmasAreSpecifiedInPhysicalUnits () const

virtual void	SmoothingSigmasAreSpecifiedInPhysicalUnitsOn ()

virtual void	SmoothingSigmasAreSpecifiedInPhysicalUnitsOff ()

virtual DecoratedOutputTransformType *	GetOutput ()

virtual const DecoratedOutputTransformType *	GetOutput () const

virtual void	SetInPlace (bool _arg)

virtual bool	GetInPlace () const

virtual void	InPlaceOn ()

virtual void	InPlaceOff ()

virtual void	InitializeCenterOfLinearOutputTransformOn ()

virtual void	InitializeCenterOfLinearOutputTransformOff ()

virtual void	SetInitializeCenterOfLinearOutputTransform (bool _arg)

virtual bool	GetInitializeCenterOfLinearOutputTransform () const

Public Member Functions inherited from itk::ProcessObject
virtual void	AbortGenerateDataOff ()

virtual void	AbortGenerateDataOn ()

virtual void	EnlargeOutputRequestedRegion (DataObject *)

virtual const bool &	GetAbortGenerateData () const

DataObjectPointerArray	GetIndexedInputs ()

DataObjectPointerArray	GetIndexedOutputs ()

NameArray	GetInputNames () const

DataObjectPointerArray	GetInputs ()

MultiThreaderType *	GetMultiThreader () const

DataObjectPointerArraySizeType	GetNumberOfIndexedInputs () const

DataObjectPointerArraySizeType	GetNumberOfIndexedOutputs () const

DataObjectPointerArraySizeType	GetNumberOfInputs () const

DataObjectPointerArraySizeType	GetNumberOfOutputs () const

virtual DataObjectPointerArraySizeType	GetNumberOfValidRequiredInputs () const

NameArray	GetOutputNames () const

DataObjectPointerArray	GetOutputs ()

virtual const float &	GetProgress () const

NameArray	GetRequiredInputNames () const

bool	HasInput (const DataObjectIdentifierType &key) const

bool	HasOutput (const DataObjectIdentifierType &key) const

virtual DataObjectPointer	MakeOutput (const DataObjectIdentifierType &)

virtual void	PrepareOutputs ()

virtual void	PropagateRequestedRegion (DataObject *output)

virtual void	ResetPipeline ()

virtual void	SetAbortGenerateData (bool _arg)

void	SetMultiThreader (MultiThreaderType *threader)

virtual void	Update ()

virtual void	UpdateLargestPossibleRegion ()

virtual void	UpdateOutputData (DataObject *output)

virtual void	UpdateOutputInformation ()

void	UpdateProgress (float progress)

virtual void	SetReleaseDataFlag (bool flag)

virtual bool	GetReleaseDataFlag () const

void	ReleaseDataFlagOn ()

void	ReleaseDataFlagOff ()

virtual void	SetReleaseDataBeforeUpdateFlag (bool _arg)

virtual const bool &	GetReleaseDataBeforeUpdateFlag () const

virtual void	ReleaseDataBeforeUpdateFlagOn ()

virtual void	ReleaseDataBeforeUpdateFlagOff ()

virtual void	SetNumberOfWorkUnits (ThreadIdType _arg)

virtual const ThreadIdType &	GetNumberOfWorkUnits () const

Public Member Functions inherited from itk::Object
unsigned long	AddObserver (const EventObject &event, Command *)

unsigned long	AddObserver (const EventObject &event, Command *) const

virtual void	DebugOff () const

virtual void	DebugOn () const

Command *	GetCommand (unsigned long tag)

bool	GetDebug () const

MetaDataDictionary &	GetMetaDataDictionary ()

const MetaDataDictionary &	GetMetaDataDictionary () const

virtual ModifiedTimeType	GetMTime () const

virtual const TimeStamp &	GetTimeStamp () const

bool	HasObserver (const EventObject &event) const

void	InvokeEvent (const EventObject &)

void	InvokeEvent (const EventObject &) const

virtual void	Modified () const

void	Register () const override

void	RemoveAllObservers ()

void	RemoveObserver (unsigned long tag)

void	SetDebug (bool debugFlag) const

void	SetReferenceCount (int) override

void	UnRegister () const noexceptoverride

void	SetMetaDataDictionary (const MetaDataDictionary &rhs)

void	SetMetaDataDictionary (MetaDataDictionary &&rrhs)

virtual void	SetObjectName (std::string _arg)

virtual const std::string &	GetObjectName () const

Public Member Functions inherited from itk::LightObject
virtual void	Delete ()

virtual int	GetReferenceCount () const

	itkCloneMacro (Self)

void	Print (std::ostream &os, Indent indent=0) const

Static Public Member Functions
static Pointer	New ()

Static Public Member Functions inherited from itk::ImageRegistrationMethodv4< TFixedImage, TMovingImage, TOutputTransform, TVirtualImage, TPointSet >
static Pointer	New ()

Static Public Member Functions inherited from itk::Object
static bool	GetGlobalWarningDisplay ()

static void	GlobalWarningDisplayOff ()

static void	GlobalWarningDisplayOn ()

static Pointer	New ()

static void	SetGlobalWarningDisplay (bool flag)

Static Public Member Functions inherited from itk::LightObject
static void	BreakOnError ()

static Pointer	New ()

Static Public Attributes
static constexpr unsigned int	ImageDimension = TFixedImage::ImageDimension

Static Public Attributes inherited from itk::ImageRegistrationMethodv4< TFixedImage, TMovingImage, TOutputTransform, TVirtualImage, TPointSet >
static constexpr unsigned int	ImageDimension = TFixedImage::ImageDimension

Protected Member Functions
virtual DisplacementFieldPointer	ComputeMetricGradientField (const FixedImagesContainerType, const PointSetsContainerType, const TransformBaseType , const MovingImagesContainerType, const PointSetsContainerType, const TransformBaseType , const FixedImageMasksContainerType, const MovingImageMasksContainerType, MeasureType &)

virtual DisplacementFieldPointer	ComputeUpdateField (const FixedImagesContainerType, const PointSetsContainerType, const TransformBaseType , const MovingImagesContainerType, const PointSetsContainerType, const TransformBaseType , const FixedImageMasksContainerType, const MovingImageMasksContainerType, MeasureType &)

virtual DisplacementFieldPointer	GaussianSmoothDisplacementField (const DisplacementFieldType *, const RealType)

void	GenerateData () override

void	InitializeRegistrationAtEachLevel (const SizeValueType) override

virtual DisplacementFieldPointer	InvertDisplacementField (const DisplacementFieldType , const DisplacementFieldType =nullptr)

void	PrintSelf (std::ostream &os, Indent indent) const override

virtual DisplacementFieldPointer	ScaleUpdateField (const DisplacementFieldType *)

virtual void	StartOptimization ()

	SyNImageRegistrationMethod ()

	~SyNImageRegistrationMethod () override=default

Protected Member Functions inherited from itk::ImageRegistrationMethodv4< TFixedImage, TMovingImage, TOutputTransform, TVirtualImage, TPointSet >
virtual void	AllocateOutputs ()

virtual VirtualImageBaseConstPointer	GetCurrentLevelVirtualDomainImage ()

	ImageRegistrationMethodv4 ()

virtual void	SetMetricSamplePoints ()

	~ImageRegistrationMethodv4 () override=default

Protected Member Functions inherited from itk::ProcessObject
virtual void	AddInput (DataObject *input)

void	AddOptionalInputName (const DataObjectIdentifierType &)

void	AddOptionalInputName (const DataObjectIdentifierType &, DataObjectPointerArraySizeType idx)

virtual void	AddOutput (DataObject *output)

bool	AddRequiredInputName (const DataObjectIdentifierType &)

bool	AddRequiredInputName (const DataObjectIdentifierType &, DataObjectPointerArraySizeType idx)

virtual void	CacheInputReleaseDataFlags ()

virtual void	GenerateInputRequestedRegion ()

virtual void	GenerateOutputInformation ()

virtual void	GenerateOutputRequestedRegion (DataObject *output)

DataObject *	GetInput (const DataObjectIdentifierType &key)

const DataObject *	GetInput (const DataObjectIdentifierType &key) const

virtual const DataObjectPointerArraySizeType &	GetNumberOfRequiredInputs () const

virtual const DataObjectPointerArraySizeType &	GetNumberOfRequiredOutputs () const

bool	IsIndexedInputName (const DataObjectIdentifierType &) const

bool	IsIndexedOutputName (const DataObjectIdentifierType &) const

bool	IsRequiredInputName (const DataObjectIdentifierType &) const

DataObjectPointerArraySizeType	MakeIndexFromInputName (const DataObjectIdentifierType &name) const

DataObjectPointerArraySizeType	MakeIndexFromOutputName (const DataObjectIdentifierType &name) const

DataObjectIdentifierType	MakeNameFromInputIndex (DataObjectPointerArraySizeType idx) const

DataObjectIdentifierType	MakeNameFromOutputIndex (DataObjectPointerArraySizeType idx) const

virtual void	PopBackInput ()

virtual void	PopFrontInput ()

	ProcessObject ()

virtual void	PropagateResetPipeline ()

virtual void	PushBackInput (const DataObject *input)

virtual void	PushFrontInput (const DataObject *input)

virtual void	ReleaseInputs ()

virtual void	RemoveInput (const DataObjectIdentifierType &key)

virtual void	RemoveInput (DataObjectPointerArraySizeType)

virtual void	RemoveOutput (const DataObjectIdentifierType &key)

virtual void	RemoveOutput (DataObjectPointerArraySizeType idx)

bool	RemoveRequiredInputName (const DataObjectIdentifierType &)

virtual void	RestoreInputReleaseDataFlags ()

virtual void	SetInput (const DataObjectIdentifierType &key, DataObject *input)

virtual void	SetNthInput (DataObjectPointerArraySizeType num, DataObject *input)

virtual void	SetNthOutput (DataObjectPointerArraySizeType num, DataObject *output)

void	SetNumberOfIndexedInputs (DataObjectPointerArraySizeType num)

void	SetNumberOfIndexedOutputs (DataObjectPointerArraySizeType num)

virtual void	SetNumberOfRequiredInputs (DataObjectPointerArraySizeType)

virtual void	SetNumberOfRequiredOutputs (DataObjectPointerArraySizeType _arg)

virtual void	SetOutput (const DataObjectIdentifierType &key, DataObject *output)

virtual void	SetPrimaryInput (DataObject *input)

virtual void	SetPrimaryOutput (DataObject *output)

void	SetRequiredInputNames (const NameArray &)

virtual void	VerifyInputInformation () ITKv5_CONST

virtual void	VerifyPreconditions () ITKv5_CONST

	~ProcessObject () override

DataObject *	GetInput (DataObjectPointerArraySizeType idx)

const DataObject *	GetInput (DataObjectPointerArraySizeType idx) const

DataObject *	GetPrimaryInput ()

const DataObject *	GetPrimaryInput () const

virtual void	SetPrimaryInputName (const DataObjectIdentifierType &key)

virtual const char *	GetPrimaryInputName () const

DataObject *	GetOutput (const DataObjectIdentifierType &key)

const DataObject *	GetOutput (const DataObjectIdentifierType &key) const

virtual void	SetPrimaryOutputName (const DataObjectIdentifierType &key)

virtual const char *	GetPrimaryOutputName () const

DataObject *	GetOutput (DataObjectPointerArraySizeType idx)

const DataObject *	GetOutput (DataObjectPointerArraySizeType idx) const

DataObject *	GetPrimaryOutput ()

const DataObject *	GetPrimaryOutput () const

Protected Member Functions inherited from itk::Object
	Object ()

bool	PrintObservers (std::ostream &os, Indent indent) const

virtual void	SetTimeStamp (const TimeStamp &time)

	~Object () override

Protected Member Functions inherited from itk::LightObject
virtual LightObject::Pointer	InternalClone () const

	LightObject ()

virtual void	PrintHeader (std::ostream &os, Indent indent) const

virtual void	PrintTrailer (std::ostream &os, Indent indent) const

virtual	~LightObject ()

Protected Attributes
bool	m_AverageMidPointGradients { false }

RealType	m_ConvergenceThreshold { static_cast<RealType>(1.0e-6) }

unsigned int	m_ConvergenceWindowSize { 10 }

bool	m_DownsampleImagesForMetricDerivatives { true }

OutputTransformPointer	m_FixedToMiddleTransform { nullptr }

RealType	m_LearningRate { 0.25 }

OutputTransformPointer	m_MovingToMiddleTransform { nullptr }

NumberOfIterationsArrayType	m_NumberOfIterationsPerLevel

Protected Attributes inherited from itk::ImageRegistrationMethodv4< TFixedImage, TMovingImage, TOutputTransform, TVirtualImage, TPointSet >
CompositeTransformPointer	m_CompositeTransform

RealType	m_CurrentConvergenceValue

SizeValueType	m_CurrentIteration

SizeValueType	m_CurrentLevel

RealType	m_CurrentMetricValue

int	m_CurrentRandomSeed

int	m_FirstImageMetricIndex

FixedImageMasksContainerType	m_FixedImageMasks

PointSetsContainerType	m_FixedPointSets

FixedImagesContainerType	m_FixedSmoothImages

bool	m_IsConverged

MetricPointer	m_Metric

MetricSamplingPercentageArrayType	m_MetricSamplingPercentagePerLevel

MetricSamplingStrategyType	m_MetricSamplingStrategy

MovingImageMasksContainerType	m_MovingImageMasks

PointSetsContainerType	m_MovingPointSets

MovingImagesContainerType	m_MovingSmoothImages

SizeValueType	m_NumberOfFixedObjects

SizeValueType	m_NumberOfLevels

SizeValueType	m_NumberOfMetrics

SizeValueType	m_NumberOfMovingObjects

OptimizerPointer	m_Optimizer

OptimizerWeightsType	m_OptimizerWeights

bool	m_OptimizerWeightsAreIdentity

OutputTransformPointer	m_OutputTransform

int	m_RandomSeed

bool	m_ReseedIterator

std::vector < ShrinkFactorsPerDimensionContainerType >	m_ShrinkFactorsPerLevel

bool	m_SmoothingSigmasAreSpecifiedInPhysicalUnits

SmoothingSigmasArrayType	m_SmoothingSigmasPerLevel

TransformParametersAdaptorsContainerType	m_TransformParametersAdaptorsPerLevel

VirtualImagePointer	m_VirtualDomainImage

Protected Attributes inherited from itk::ProcessObject
TimeStamp	m_OutputInformationMTime

bool	m_Updating

Protected Attributes inherited from itk::LightObject
std::atomic< int >	m_ReferenceCount

Private Attributes
RealType	m_GaussianSmoothingVarianceForTheTotalField { 0.5 }

RealType	m_GaussianSmoothingVarianceForTheUpdateField { 3.0 }