[Insight-users] Problem with BSpline Registration with Mattes-MI

Serena Fabbri fabbri at u.washington.edu
Tue Jul 7 13:05:47 EDT 2009


Hi All,

I am registering brain MRI and CT image with BSpline (Non Rigid Registration), Mattes MI and LBFGSB 
optimization.

fixed=MRI   (176,256,160); (1,1,1)mm; (0,0,0)mm
moving=CT (176,256,160); (1,1,1)mm; (0,0,0)mm

CT image is been previously Rigid registered to MRI

I have started with 6x6x6 grid (3x3x3 nodes on the fixed image), MI sample =20% statistics and the 
registered image is pretty good.
In order to improve the result I have used a fine grid: 13x13x13 (10x10x10 nodes on the fixed 
image), MI sample =20% statistics, and the result is:
in general the registration is good because some details are better overlapped, but  the slices 
containing the nose structures are distorted. In particular nasal septum is deviated in the left side and 
the other bone appears too much smoothed.
I have read some previous e-mails (http://www.itk.org/pipermail/insight-users/2008-
December/028417.html) in archives and an Ibanez advice was to check if there are enough samples 
for population every cell of the BSpline grid. I think that it is enough samples because i get the same 
result with 50% samples.

I have tried to set different number of nodes in x and y direction. I have used 6x13x13 grid and 20% 
sample too, and i get exactly the same registered image previous described (Below I put the Iteration-
MattesMI value ).


can anyone give me some advice?
maybe it is necessary to set different number of nodes in x and y direction. 
Could it be a reasonable explanation?

any suggestion will be appreciate.

Thanks.

Serena.


Iter  MattesMI
0   -0.350671   
0   -0.351995   
0   -0.357607   
0   -0.377623   
0   -0.402784   
0   -0.402784   
1   -0.435035   
1   -0.435035   
2   -0.430811   
2   -0.466589   
2   -0.466589   
3   -0.491583   
3   -0.491583   
4   -0.499865   
4   -0.499865   
5   -0.53353   
5   -0.53353   
6   -0.533558   
6   -0.543796   
6   -0.543796   
7   -0.559133   
7   -0.559133   
8   -0.567699   
8   -0.567699   
9   -0.577058   
9   -0.577058   
10   -0.586574   
10   -0.586574   
11   -0.59515   
11   -0.59515   
12   -0.600187   
12   -0.600187   
13   -0.608752   
13   -0.608752   
14   -0.614033   
14   -0.614033   
15   -0.619695   
15   -0.619695   
16   -0.623183   
16   -0.623183   
17   -0.627047   
17   -0.627047   
18   -0.630555   
18   -0.630555   
19   -0.634089   
19   -0.634089   
20   -0.638822   
20   -0.638822   
21   -0.642822   
21   -0.642822   
22   -0.648013   
22   -0.648013   
23   -0.651278   
23   -0.651278   
24   -0.65333   
24   -0.65333   
25   -0.656569   
25   -0.656569   
26   -0.659193   
26   -0.659193   
27   -0.661128   
27   -0.661128   
28   -0.663331   
28   -0.663331   
29   -0.66513   
29   -0.66513   
30   -0.666392   
30   -0.666392   
31   -0.667716   
31   -0.667716   
32   -0.668881   
32   -0.668881   
33   -0.669772   
33   -0.669772   
34   -0.671548   
34   -0.671548   
35   -0.672711   
35   -0.672711   
36   -0.674103   
36   -0.674103   
37   -0.674998   
37   -0.674998   
38   -0.676283   
38   -0.676283   
39   -0.677051   
39   -0.677051   
40   -0.678061   
40   -0.678061   
41   -0.678757   
41   -0.678757   
42   -0.67975   
42   -0.67975   
43   -0.680577   
43   -0.680577   
44   -0.681572   
44   -0.681572   
45   -0.682606   
45   -0.682606   
46   -0.683061   
46   -0.683061   
47   -0.683633   
47   -0.683633   
48   -0.684106   
48   -0.684106   
49   -0.684759   
49   -0.684759   
50   -0.685085   
50   -0.685085   
51   -0.685878   
51   -0.685878   
52   -0.686366   
52   -0.686366   
53   -0.686903   
53   -0.686903   
54   -0.687805   
54   -0.687805   
55   -0.688129   
55   -0.688129   
56   -0.688648   
56   -0.688648   
57   -0.689047   
57   -0.689047   
58   -0.689372   
58   -0.689372   
59   -0.690139   
59   -0.690139   
60   -0.690221   
60   -0.690221   
61   -0.690577   
61   -0.690577   
62   -0.69085   
62   -0.69085   
63   -0.691391   
63   -0.691391   
64   -0.691557   
64   -0.691557   
65   -0.691489   
65   -0.691692   
65   -0.691692   
66   -0.691924   
66   -0.691924   
67   -0.692416   
67   -0.692416   
68   -0.692831   
68   -0.692831   
69   -0.692933   
69   -0.692933   
70   -0.693209   
70   -0.693209   
71   -0.693661   
71   -0.693661   
72   -0.69374   
72   -0.69374   
73   -0.694059   
73   -0.694059   
74   -0.694317   
74   -0.694317   
75   -0.694812   
75   -0.694812   
76   -0.694946   
76   -0.694946   
77   -0.695411   
77   -0.695411   
78   -0.695788   
78   -0.695788   
79   -0.695936   
79   -0.695936   
80   -0.69627   
80   -0.69627   
81   -0.696409   
81   -0.696409   
82   -0.696002   
82   -0.696418   
82   -0.696418   
83   -0.696533   
83   -0.696533   
84   -0.697105   
84   -0.697105   
85   -0.697287   
85   -0.697287   
86   -0.697609   
86   -0.697609   
87   -0.697957   
87   -0.697957   
88   -0.697482   
88   -0.697993   
88   -0.697993   
89   -0.698045   
89   -0.698045   
90   -0.698389   
90   -0.698389   
91   -0.699091   
91   -0.699091   
92   -0.699072   
92   -0.699127   
92   -0.699127   
93   -0.699169   
93   -0.699169   
94   -0.699422   
94   -0.699422   
95   -0.699545   
95   -0.699545   
96   -0.700181   
96   -0.700181   
97   -0.70052   
97   -0.70052   
98   -0.700755   
98   -0.700755   
99   -0.700869   
99   -0.700869   
100   -0.699019   
100   -0.700874   
100   -0.700874   
101   -0.697901   
101   -0.700846   
101   -0.700874   
101   -0.700875   
101   -0.700875   
101   -0.700874   
101   -0.700875   
101   -0.700875   
101   -0.700875   
101   -0.700875   
101   -0.700875   
102   -0.682951   
102   -0.700818   
102   -0.700878   
102   -0.700878   
103   -0.700522   
103   -0.700962   
103   -0.700962   
104   -0.700956   
104   -0.701143   
104   -0.701143   
105   -0.700847   
105   -0.701264   
105   -0.701264   
106   -0.699357   
106   -0.701293   
106   -0.701293   
107   -0.700802   
107   -0.701318   
107   -0.701318   
108   -0.701101   
108   -0.701454   
108   -0.701454   
109   -0.701117   
109   -0.701525   
109   -0.701525   
110   -0.700914   
110   -0.701622   
110   -0.701622   
111   -0.701429   
111   -0.701679   
111   -0.701679   
112   -0.702049   
112   -0.702049   
113   -0.702067   
113   -0.702067   
114   -0.702424   
114   -0.702424   
115   -0.702911   
115   -0.702911   
116   -0.702993   
116   -0.702993   
117   -0.703354   
117   -0.703354   
118   -0.70348   
118   -0.70348   
119   -0.703623   
119   -0.703623   
120   -0.703758   
120   -0.703758   
121   -0.703861   
121   -0.703861   
122   -0.703992   
122   -0.703992   
123   -0.704031   
123   -0.704031   
124   -0.704308   
124   -0.704308   
125   -0.704431   
125   -0.704431   
126   -0.704565   
126   -0.704565   
127   -0.704793   
127   -0.704793   
128   -0.704626   
128   -0.704884   
128   -0.704884   
129   -0.7044   
129   -0.704907   
129   -0.704907   
130   -0.705365   
130   -0.705365   
131   -0.705579   
131   -0.705579   
132   -0.705919   
132   -0.705919   
133   -0.706196   
133   -0.706196   
134   -0.706419   
134   -0.706419   
135   -0.706565   
135   -0.706565   
136   -0.706604   
136   -0.706604   
137   -0.706731   
137   -0.706731   
138   -0.706708   
138   -0.706768   
138   -0.706768   
139   -0.706699   
139   -0.70692   
139   -0.70692   
140   -0.706833   
140   -0.706975   
140   -0.706975   
141   -0.706896   
141   -0.707044   
141   -0.707044   
142   -0.706378   
142   -0.70706   
142   -0.70706   
143   -0.705602   
143   -0.707069   
143   -0.706376   
143   -0.707055   
143   -0.707068   
143   -0.707069   
143   -0.707069   
143   -0.707069   
144   -0.0399776   
144   -0.677537   
144   -0.706919   
144   -0.707062   
144   -0.707068   
144   -0.707069   
144   -0.707069   
144   -0.707069   
144   -0.707069   
144   -0.707069   
144   -0.707069   
144   -0.707069   
144   -0.707069   
145   -0.614007









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